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Cox5a Gene Detail
Summary
  • Symbol
    Cox5a
  • Name
    cytochrome c oxidase subunit Va
  • Synonyms
    CcOX
  • Feature Type
    protein coding gene
  • IDs
    MGI:88474
    NCBI Gene: 12858
  • Gene Overview
    MyGene.info: COX5A
Location & Maps
more
  • Sequence Map
    Chr9:57521232-57532424 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11193 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 31.05 cM
  • Mapping Data
    10 experiments
Homology
more
  • Human Ortholog
    COX5A, cytochrome c oxidase subunit 5A
  • Vertebrate Orthologs
    11
  • Human Ortholog
    COX5A, cytochrome c oxidase subunit 5A
    Orthology source: HGNC, HomoloGene
  • Synonyms
    COX, COX-VA, VA
  • Links
    NCBI Gene ID: 9377
    neXtProt AC: NX_P20674

  • Chr Location
    15q24.1; chr15:74920275-74938154 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    35
  • Gene trapped
    35
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000000088 Ensembl Gene Model | MGI Sequence Detail 11193 C57BL/6J ±  kb
transcript ENSMUST00000000090 Ensembl | MGI Sequence Detail 690 Not Applicable  
polypeptide ENSMUSP00000000090 Ensembl | MGI Sequence Detail 146 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    29 from dbSNP Build 142
  • PCR
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000005779 cytochrome c oxidase subunit 5A, mitochondrial
  • InterPro Domains
    IPR003204 Cytochrome c oxidase, subunit Va/VI
Molecular
Reagents
less
  • All nucleic 357
    cDNA 353
    Primer pair 4

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-2098, MGI:2144051
References
more
  • Summaries
    All 57
    Developmental Gene Expression 7
    Gene Ontology 11
    Phenotypes 5
  • Earliest
    J:20269 Wright RM, et al., Isolation and sequence of the structural gene for cytochrome c oxidase subunit VI from Saccharomyces cerevisiae. J Biol Chem. 1984 Dec 25;259(24):15401-7
  • Latest
    J:195548 Brody MJ, et al., Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy. PLoS One. 2012;7(12):e51621

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory