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Col10a1
Gene Detail
Symbol

Name
ID
Col10a1
collagen, type X, alpha 1
MGI:88445
Synonyms
Col10, Col10a-1
Feature Type
protein coding gene
Genetic Map
Chromosome 10
18.85 cM, cytoband B1-B3
Detailed Genetic Map ± 1 cM


Mapping data(8)
Sequence Map
Chr10:34389981-34397085 bp, + strand
From VEGA annotation of GRCm38

  7105 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55466  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Col10a1

Human
homologs
Human Homolog COL10A1, collagen, type X, alpha 1
NCBI Gene ID 1300
neXtProt AC  NX_Q03692
Human Chr (Location)  6q21-q22; chr6:116118909-116158989 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human COL10A1
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for targeted null mutations may exhibit abnormal trabecular bone, thinner growth plate resting zone and articular cartilage, and altered bone content.
 
Human Diseases Modeled Using Mouse Col10a1 (1)    Alleles Annotated to Human Diseases(1)    Phenotype Images(2)
Interactions
Col10a1 interacts with 203 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Component cell cortex, collagen trimer, ...
External Resources: FuncBase
Expression
Literature Summary: (328 records)
Data Summary: Results (285)    Tissues (98)    Images (165)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 21
RNA in situ 249
Northern blot 5
RT-PCR 10
cDNA source data(18)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(63) Genomic(19) cDNA(24) Primer pair(6) Other(14)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000022505 (Evidence)
Ensembl Gene ModelENSMUSG00000039462 (Evidence)
Entrez Gene12813 (Evidence)
UniGene443177
DFCITC1586596, TC1685686
DoTSDT.110588399, DT.99850740
NIA Mouse Gene IndexU011398
Consensus CDS ProjectCCDS23780.1
International Mouse Knockout Project StatusCol10a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022505 VEGA Gene Model | MGI Sequence Detail 7105 C57BL/6J ±  kb
transcript OTTMUST00000053879 VEGA | MGI Sequence Detail 3130 Not Applicable 
polypeptide OTTMUSP00000025645 VEGA | MGI Sequence Detail 680 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(2) UniProt(1)
Polymorphisms
RFLP(2) : SNPs within 2kb(41 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008160 Collagen triple helix repeat
InterPro IPR001073 Complement C1q protein
InterPro IPR008983 Tumour necrosis factor-like domain
Protein Ontology PR:000005693 collagen alpha-1(X) chain
References
(Earliest) J:717 Elima K, et al., Specific hybridization probes for mouse alpha 2(IX) and alpha 1(X) collagen mRNAs. Biochim Biophys Acta. 1992 Feb 28;1130(1):78-80
(Latest) J:207837 Schmid R, et al., Redundancy in regulation of chondrogenesis in MIA/CD-RAP-deficient mice. Mech Dev. 2014 Feb;131:24-34
All references(380)
Disease annotation references (1)
Other
accession IDs
MGD-MRK-2051, MGD-MRK-2052

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory