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Cnbp
Gene Detail
Symbol

Name
ID
Cnbp
cellular nucleic acid binding protein
MGI:88431
Synonyms
Znf9
Feature Type
protein coding gene
Genetic Map
Chromosome 6
39.13 cM, cytoband D1-D2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:87843082-87851106 bp, - strand
From VEGA annotation of GRCm38

  8025 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2567  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: cellular nucleic acid-binding protein
Gene Tree: Cnbp

Human
homologs
Human Homolog CNBP, CCHC-type zinc finger, nucleic acid binding protein
NCBI Gene ID 7555
neXtProt AC  NX_P62633
Human Synonyms  CNBP1, DM2, PROMM, RNF163, ZCCHC22, ZNF9
Human Chr (Location)  3q21; chr3:129167815-129183967 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human CNBP
Mutations,
alleles, and
phenotypes
All mutations/alleles(93) : Gene trapped(88) Targeted(4) Transgenic(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a retroviral insertional mutation exhibit reduced embryo size and embryonic lethality associated with anterior patterning defects and severe forebrain truncation. About 40% of heterozygotes exhibit reduced embryo size, various craniofacial defects, and neonatal death.
 
Interactions
Cnbp interacts with 299 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process positive regulation of cell proliferation, positive regulation of transcription, DNA-templated, ...
Component cytoplasm, cytosol, ...
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (17 records)
Data Summary: Results (151)    Tissues (135)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 102
RT-PCR 49
cDNA source data(32)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(37) Genomic(1) cDNA(33) Primer pair(3)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000023465 (Evidence)
Ensembl Gene ModelENSMUSG00000030057 (Evidence)
Entrez Gene12785 (Evidence)
DFCITC1573850, TC1575530, TC1632422, TC1778073
DoTSDT.101195061, DT.101195066, DT.101223282, DT.55215912, DT.91318288, DT.99866349
NIA Mouse Gene IndexU027586
Consensus CDS ProjectCCDS51841.1
International Mouse Knockout Project StatusCnbp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023465 VEGA Gene Model | MGI Sequence Detail 8025 C57BL/6J ±  kb
transcript OTTMUST00000057063 VEGA | MGI Sequence Detail 1708 Not Applicable 
polypeptide OTTMUSP00000027487 VEGA | MGI Sequence Detail 177 Not Applicable 

For the selected sequences
All sequences(84) RefSeq(8) UniProt(11)
Polymorphisms
SNPs within 2kb(15 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001878 Zinc finger, CCHC-type
Protein Ontology PR:000005627 cellular nucleic acid-binding protein
References
(Earliest) J:21465 Warden CH, et al., Mouse cellular nucleic acid binding proteins: a highly conserved family identified by genetic mapping and sequencing. Genomics. 1994 Nov 1;24(1):14-9
(Latest) J:209112 Shimizu H, et al., The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
All references(59)
Other
accession IDs
MGD-MRK-2033, MGI:2141361

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory