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Cma2
Gene Detail
Symbol

Name
ID
Cma2
chymase 2, mast cell
MGI:88426
Feature Type
protein coding gene
Genetic Map
Chromosome 14
28.19 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr14:55971428-55973995 bp, + strand
From Ensembl annotation of GRCm38

  2568 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:115745  Vertebrate Homology Class
2 mouse

Protein SuperFamily: trypsin
Gene Tree: Cma2

Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cma2 interacts with 27 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process proteolysis
Component secretory granule
Function serine-type endopeptidase activity
External Resources: FuncBase
Expression
cDNA source data(5)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000068289 (Evidence)
Entrez Gene545055 (Evidence)
UniGene378966
Consensus CDS ProjectCCDS27136.1
International Mouse Knockout Project StatusCma2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000068289 Ensembl Gene Model | MGI Sequence Detail 2568 C57BL/6J ±  kb
transcript ENSMUST00000089555 Ensembl | MGI Sequence Detail 947 Not Applicable 
polypeptide ENSMUSP00000086984 Ensembl | MGI Sequence Detail 246 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(6) UniProt(4)
Polymorphisms
SNPs within 2kb(127 from dbSNP Build 137)    SNPs within 2kb including multiple locations(227)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
References
(Earliest) J:1144 Chu W, et al., Molecular cloning and characterization of mouse mast cell chymases. Biochim Biophys Acta. 1992 May 22;1121(1-2):83-7
All references(12)
Other
accession IDs
MGD-MRK-2026

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory