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F13b Gene Detail
Summary
  • Symbol
    F13b
  • Name
    coagulation factor XIII, beta subunit
  • Synonyms
    Cf13b, Cf-13b
  • Feature Type
    protein coding gene
  • IDs
    MGI:88379
    NCBI Gene: 14060
  • Gene Overview
    MyGene.info: F13B
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:139501702-139523752 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 61.57 cM, cytoband F
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    213 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88379
protein coding gene Chr1:139501547-139523758 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016554
protein coding gene Chr1:143569114-143592016 (+)
A/J MGP_AJ_G0016537
protein coding gene Chr1:137988396-138010871 (+)
AKR/J MGP_AKRJ_G0016502
protein coding gene Chr1:142156166-142180082 (+)
BALB/cJ MGP_BALBcJ_G0016497
protein coding gene Chr1:138349789-138373012 (+)
C3H/HeJ MGP_C3HHeJ_G0016323
protein coding gene Chr1:142242497-142269098 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016958
protein coding gene Chr1:148599025-148622241 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014669
protein coding gene Chr1:131062012-131084557 (+)
CAST/EiJ MGP_CASTEiJ_G0015903
protein coding gene Chr1:141423167-141446852 (+)
CBA/J MGP_CBAJ_G0016296
protein coding gene Chr1:153730501-153760093 (+)
DBA/2J MGP_DBA2J_G0016402
protein coding gene Chr1:136995840-137017067 (+)
FVB/NJ MGP_FVBNJ_G0016401
protein coding gene Chr1:135630850-135653740 (+)
LP/J MGP_LPJ_G0016473
protein coding gene Chr1:144670019-144691758 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016426
protein coding gene Chr1:159377774-159411331 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016994
protein coding gene Chr1:141956364-141980543 (+)
PWK/PhJ MGP_PWKPhJ_G0015689
protein coding gene Chr1:136078383-136102465 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015476
protein coding gene Chr1:140901244-140922947 (+)
WSB/EiJ MGP_WSBEiJ_G0015966
protein coding gene Chr1:141959751-141983877 (+)



Homology
more
  • Human Ortholog
    F13B, coagulation factor XIII B chain
  • Vertebrate Orthologs
    7
  • Human Ortholog
    F13B, coagulation factor XIII B chain
    Orthology source: HGNC, HomoloGene
  • Synonyms
    FXIIIB
  • Links
    NCBI Gene ID: 2165
    neXtProt AC: NX_P05160
    UniProt: P05160

  • Chr Location
    1q31.3; chr1:197038741-197067267 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human F13B associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display increased bleeding time.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026368 Ensembl Gene Model | MGI Sequence Detail 22051 C57BL/6J ±  kb
transcript ENSMUST00000027615 Ensembl | MGI Sequence Detail 2379 Not Applicable  
polypeptide ENSMUSP00000027615 Ensembl | MGI Sequence Detail 669 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 23
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-1945, MGD-MRK-1951, MGI:1309530
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory