Ces1g
Gene Detail

Symbol Name ID

Ces1g carboxylesterase 1G MGI:88378

Synonyms

Ces1, Ces-1, Ses-1

Feature Type

protein coding gene

Genetic Map

Chromosome 8

45.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr8:93302369-93337308 bp, - strand From VEGA annotation of GRCm38   34940 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:128394  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle

Protein SuperFamily: esterase, acetylcholinesterase type
Gene Tree: Ces1g

Human homologs

Human Homolog		CES1, carboxylesterase 1
NCBI Gene ID		1066
neXtProt AC		NX_P23141
Human Synonyms		ACAT, CE-1, CEH, CES2, hCE-1, HMSE, HMSE1, PCE-1, REH, SES1, TGH
Human Chr (Location)		16q22.2; chr16:55836763-55867075 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human CES1

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Component	endoplasmic reticulum
Function	carboxylesterase activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (61)    Tissues (8)    Images (23)
Theiler Stages: 23

Assay Type	Results
RNA in situ	61

cDNA source data(27)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(29) cDNA(28) Other(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000040118 (Evidence)
Ensembl Gene Model	ENSMUSG00000057074 (Evidence)
Entrez Gene	12623 (Evidence)
UniGene	22720
DFCI	TC1584507
DoTS	DT.110854874, DT.110854965, DT.525710
NIA Mouse Gene Index	U030104
EC	3.1.1.1
Consensus CDS Project	CCDS22531.1
International Mouse Knockout Project Status	Ces1g

Sequences

Length	Strain/Species
genomic	OTTMUSG00000040118	VEGA Gene Model | MGI Sequence Detail	34940	C57BL/6J
transcript	OTTMUST00000060226	VEGA | MGI Sequence Detail	2388	Not Applicable
polypeptide	OTTMUSP00000029370	VEGA | MGI Sequence Detail	565	Not Applicable

All sequences(24) RefSeq(2) UniProt(2)

Polymorphisms

RFLP(1) : SNPs(145 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002018	Carboxylesterase, type B
InterPro	IPR019826	Carboxylesterase type B, active site
InterPro	IPR019819	Carboxylesterase type B, conserved site
Protein Ontology	PR:000005365	liver carboxylesterase 1

References

(Earliest) J:14958 Becker-Follmann J, et al., Assignment of human monocyte/macrophage serine esterase 1 (HMSE1) to human Chromosome 16q13-q22.1 and of its homologue to the proximal esterase cluster on mouse Chromosome 8. Cytogenet Cell Genet. 1991;58:1997
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)

Other accession IDs

MGD-MRK-14364, MGD-MRK-1943, MGD-MRK-1944