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Cd7
Gene Detail
Symbol

Name
ID
Cd7
CD7 antigen
MGI:88344
Feature Type
protein coding gene
Genetic Map
Chromosome 11
84.85 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:121036747-121039418 bp, - strand
From VEGA annotation of GRCm38

  2672 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4471  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog

HCOP human homology predictions: CD7
Protein SuperFamily: T-cell antigen CD7
Gene Tree: Cd7

Human
homologs
CD7, CD7 molecule
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 924
neXtProt AC: NX_P09564

Human Synonyms: GP40, LEU-9, Tp40, TP41

Human Chr (Location): 17q25.2-q25.3; chr17:82314865-82317604 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in a 60% increase of CD4+CD8+ thymocytes at 3 months of age.
 
Interactions
Cd7 interacts with 46 markers (Mir23a, Mir23b, Mir93, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process adaptive immune response, homeostasis of number of cells within a tissue, ...
Component extracellular exosome, integral component of membrane, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (46)    Tissues (45)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 46
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(19) Genomic(6) cDNA(12) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000004165 (Evidence)
Ensembl Gene Model ENSMUSG00000025163 (Evidence)
Entrez Gene 12516 (Evidence)
UniGene 4100
DFCI TC1584894
DoTS DT.486571
NIA Mouse Gene Index U033740
Consensus CDS Project CCDS25764.1
International Mouse Phenotyping Consortium Status Cd7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004165 VEGA Gene Model | MGI Sequence Detail 2672 C57BL/6J ±  kb
transcript OTTMUST00000009447 VEGA | MGI Sequence Detail 982 Not Applicable 
polypeptide OTTMUSP00000004600 VEGA | MGI Sequence Detail 210 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(2) UniProt(3)
Polymorphisms
RFLP(1) : SNPs within 2kb(79 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR013106 Immunoglobulin V-set
Protein Ontology PR:000001836 CD7 molecule
References
(Earliest) J:4522 Yoshikawa K, et al., Isolation and characterization of mouse CD7 cDNA. Immunogenetics. 1993;37(2):114-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)
Other
accession IDs
MGD-MRK-1870

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory