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Cd5
Gene Detail
 Symbol
Name
ID
Cd5
CD5 antigen
MGI:88340
Synonyms Ly-1, Ly-12, Ly-A, Lyt-1
Feature Type protein coding gene
Genetic Map
Chromosome 19
7.16 cM
Detailed Genetic Map ± 1 cM


Mapping data(62)
Sequence Map
Chr19:10718143-10738974 bp, - strand
From NCBI annotation of GRCm38

  20832 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7260  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: T-cell surface glycoprotein CD5
Gene Tree: Cd5

Human
homologs
Human Homolog CD5, CD5 molecule
NCBI Gene ID 921
neXtProt AC  NX_P06127
Human Synonyms  LEU1, T1
Human Chr (Location)  11q13; chr11:61102458-61127852 (+)  GRCh38
Alleles
and
phenotypes
All alleles(6) : Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene does not result in a phenotype.
 
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process apoptotic signaling pathway, T cell costimulation
Component external side of plasma membrane, fully spanning plasma membrane, ...
Function glycoprotein binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (1)    Tissues (1)   
Theiler Stages: 28
Assay TypeResults
Immunohistochemistry 1
cDNA source data(18)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(22) Genomic(2) cDNA(18) Primer pair(1) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000024669 (Evidence)
Entrez Gene12507 (Evidence)
UniGene779
DFCITC1582750
DoTSDT.97392241
NIA Mouse Gene IndexU038810
Consensus CDS ProjectCCDS29586.1
International Mouse Knockout Project StatusCd5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 12507 NCBI Gene Model | MGI Sequence Detail 20832 C57BL/6J ±  kb
transcript NM_007650 RefSeq | MGI Sequence Detail 2069 C57BL/6 
polypeptide P13379 UniProt | EBI | MGI Sequence Detail 494 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(4) UniProt(5)
Polymorphisms RFLP(4) : SNPs within 2kb(236 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001190 Speract/scavenger receptor
InterPro IPR017448 Speract/scavenger receptor-related
InterPro IPR003566 T-cell surface glycoprotein CD5
Protein Ontology PR:000001839 T-cell surface glycoprotein CD5
Graphical View of Protein Domain Structure
References (Earliest) J:5195 Itakura K, et al., Linkage groups of the theta and Ly-A loci. Nat New Biol. 1971 Mar 24;230(12):126
(Latest) J:209281 McGuire DJ, et al., CD5 enhances Th17-cell differentiation by regulating IFN-gamma response and RORgammat localization. Eur J Immunol. 2014 Apr;44(4):1137-42
All references(131)
Other
accession IDs
MGD-MRK-11947, MGD-MRK-11950, MGD-MRK-12073, MGD-MRK-1866

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory