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Cd5 Gene Detail
Summary
  • Symbol
    Cd5
  • Name
    CD5 antigen
  • Synonyms
    Ly-1, Ly-12, Ly-A, Lyt-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:88340
    NCBI Gene: 12507
  • Gene Overview
    MyGene.info: CD5
Location & Maps
more
  • Sequence Map
    Chr19:10718143-10738974 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      20832 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    CD5, CD5 molecule
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CD5, CD5 molecule
    Orthology source: HGNC, HomoloGene
  • Synonyms
    LEU1, T1
  • Links
    NCBI Gene ID: 921
    neXtProt AC: NX_P06127

  • Chr Location
    11q13; chr11:61102458-61127852 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotypes from 2 alleles in 3 genetic backgrounds
    10 phenotypes from multigenic genotypes
    24 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
Homozygous mutation of this gene does not result in a phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024669 Ensembl Gene Model | MGI Sequence Detail 20832 C57BL/6J ±  kb
transcript ENSMUST00000025571 Ensembl | MGI Sequence Detail 2069 Not Applicable  
polypeptide ENSMUSP00000025571 Ensembl | MGI Sequence Detail 494 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    237 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    Genomic 2
    cDNA 18
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-11947, MGD-MRK-11950, MGD-MRK-12073, MGD-MRK-1866
References
more
  • Summaries
    All 127
    Developmental Gene Expression 2
    Gene Ontology 14
    Phenotypes 24
  • Earliest
    J:5195 Itakura K, et al., Linkage groups of the theta and Ly-A loci. Nat New Biol. 1971 Mar 24;230(12):126
  • Latest
    J:209281 McGuire DJ, et al., CD5 enhances Th17-cell differentiation by regulating IFN-gamma response and RORgammat localization. Eur J Immunol. 2014 Apr;44(4):1137-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory