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Cd3g
Gene Detail
Symbol

Name
ID
Cd3g
CD3 antigen, gamma polypeptide
MGI:88333
Synonyms
Ctg3, Ctg-3, T3g
Feature Type
protein coding gene
Genetic Map
Chromosome 9
24.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(8)
Sequence Map
Chr9:44969572-44980431 bp, - strand
From VEGA annotation of GRCm38

  10860 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: T-cell surface glycoprotein CD3 delta chain
Gene Tree: Cd3g

Human
homologs
Human Homolog CD3G, CD3g molecule, gamma (CD3-TCR complex)
NCBI Gene ID 917
neXtProt AC  NX_P09693
Human Synonyms  CD3-GAMMA, IMD17, T3G
Human Chr (Location)  11q23; chr11:118344317-118353782 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human CD3G
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(2) Targeted(7)
Genomic Mutations involving Cd3g (1)
 
Mice homozygous for a knock-out allele exhibit decreased thymocyte number and T cell response.
 
Interactions
Cd3g interacts with 62 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (1)    Tissues (1)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 1
cDNA source data(28)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(38) Genomic(9) cDNA(29)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000034601 (Evidence)
Ensembl Gene ModelENSMUSG00000002033 (Evidence)
Entrez Gene12502 (Evidence)
UniGene335106
DFCITC1584247
DoTSDT.101369643, DT.492838, DT.525991
NIA Mouse Gene IndexU030789
PDB1JBJ
Consensus CDS ProjectCCDS23123.1
International Mouse Knockout Project StatusCd3g
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034601 VEGA Gene Model | MGI Sequence Detail 10860 C57BL/6J ±  kb
transcript OTTMUST00000087780 VEGA | MGI Sequence Detail 1023 Not Applicable 
polypeptide OTTMUSP00000047791 VEGA | MGI Sequence Detail 182 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(2) UniProt(7)
Polymorphisms
RFLP(2) : SNPs within 2kb(152 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015484 CD3 protein, gamma/delta subunit
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003598 Immunoglobulin subtype 2
InterPro IPR003110 Phosphorylated immunoreceptor signaling ITAM
Protein Ontology PR:000001021 CD3 gamma
References
(Earliest) J:8651 Gold DP, et al., The gene encoding the epsilon subunit of the T3/T-cell receptor complex maps to chromosome 11 in humans and to chromosome 9 in mice. Proc Natl Acad Sci U S A. 1987 Mar;84(6):1664-8
(Latest) J:210584 van Berlo JH, et al., c-kit+ cells minimally contribute cardiomyocytes to the heart. Nature. 2014 May 15;509(7500):337-41
All references(71)
Other
accession IDs
MGD-MRK-14698, MGD-MRK-1854, MGD-MRK-2212, MGD-MRK-2213

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory