About   Help   FAQ
Cd3g
Gene Detail
Symbol

Name
ID
Cd3g
CD3 antigen, gamma polypeptide
MGI:88333
Synonyms
Ctg3, Ctg-3, T3g
Feature Type
protein coding gene
Genetic Map
Chromosome 9
24.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(8)
Sequence Map
Chr9:44969572-44980431 bp, - strand
From VEGA annotation of GRCm38

  10860 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: CD3G
Protein SuperFamily: T-cell surface glycoprotein CD3 delta chain
Gene Tree: Cd3g

Human
homologs
CD3G, CD3g molecule, gamma (CD3-TCR complex)
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 917
neXtProt AC: NX_P09693

Human Synonyms: CD3-GAMMA, IMD17, T3G

Human Chr (Location): 11q23; chr11:118344316-118353782 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human CD3G

Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(2) Targeted(7)
Genomic Mutations involving Cd3g (1)
Incidental mutations (data from CvDC )
 
Mice homozygous for a knock-out allele exhibit decreased thymocyte number and T cell response.
 
Interactions
Cd3g interacts with 62 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (1)    Tissues (1)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 1
cDNA source data(28)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase cd3g    NEW 
Molecular
reagents
All nucleic(38) Genomic(9) cDNA(29)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000034601 (Evidence)
Ensembl Gene Model ENSMUSG00000002033 (Evidence)
Entrez Gene 12502 (Evidence)
UniGene 335106
DFCI TC1584247
DoTS DT.101369643, DT.492838, DT.525991
NIA Mouse Gene Index U030789
PDB 1JBJ
Consensus CDS Project CCDS23123.1
International Mouse Phenotyping Consortium Status Cd3g
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034601 VEGA Gene Model | MGI Sequence Detail 10860 C57BL/6J ±  kb
transcript OTTMUST00000087780 VEGA | MGI Sequence Detail 1023 Not Applicable 
polypeptide OTTMUSP00000047791 VEGA | MGI Sequence Detail 182 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(2) UniProt(4)
Polymorphisms
RFLP(2) : SNPs within 2kb(152 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015484 CD3 protein, gamma/delta subunit
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003598 Immunoglobulin subtype 2
InterPro IPR003110 Phosphorylated immunoreceptor signaling ITAM
Protein Ontology PR:000001021 CD3 gamma
References
(Earliest) J:8687 Krissansen GW, et al., Molecular cloning of the cDNA encoding the T3 gamma subunit of the mouse T3/T cell antigen receptor complex. J Immunol. 1987 May 15;138(10):3513-8
(Latest) J:210584 van Berlo JH, et al., c-kit+ cells minimally contribute cardiomyocytes to the heart. Nature. 2014 May 15;509(7500):337-41
All references(67)
Other
accession IDs
MGD-MRK-14698, MGD-MRK-1854, MGD-MRK-2212, MGD-MRK-2213

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/21/2015
MGI 5.22
The Jackson Laboratory