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Cd37
Gene Detail
 Symbol
Name
ID
Cd37
CD37 antigen
MGI:88330
Synonyms Tspan26
Feature Type protein coding gene
Genetic Map
Chromosome 7
29.20 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr7:45233632-45239115 bp, - strand
From VEGA annotation of GRCm38

  5484 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20422  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: tetraspanin
Gene Tree: Cd37

Human
homologs
Human Homolog CD37, CD37 molecule
NCBI Gene ID 951
neXtProt AC  NX_P11049
Human Synonyms  GP52-40, TSPAN26
Human Chr (Location)  19q13.3; chr19:49335418-49340606 (+)  GRCh38
Alleles
and
phenotypes
All alleles(130) : Gene trapped(126) Targeted(4)
 
Homozygous mutation of this gene results in reduced levels of IgG1 immunoglobulins and impaired antibody response to T cell dependent antigens.
 
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process defense response to protozoan, negative regulation of cell proliferation, ...
Component extracellular vesicular exosome, immunological synapse, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (5)    Tissues (1)    Images (5)
Theiler Stages: 23
Assay TypeResults
RNA in situ 5
cDNA source data(48)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(51) Genomic(3) cDNA(48)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000025381 (Evidence)
Ensembl Gene ModelENSMUSG00000030798 (Evidence)
Entrez Gene12493 (Evidence)
UniGene3689
DFCITC1580002, TC1591444, TC1643256
DoTSDT.101340713, DT.40159393, DT.492245, DT.97347368, DT.99851984, DT.99851986
NIA Mouse Gene IndexU028522
Consensus CDS ProjectCCDS21237.1, CCDS71958.1
International Mouse Knockout Project StatusCd37
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025381 VEGA Gene Model | MGI Sequence Detail 5484 C57BL/6J ±  kb
transcript OTTMUST00000062491 VEGA | MGI Sequence Detail 1268 Not Applicable 
polypeptide OTTMUSP00000030810 VEGA | MGI Sequence Detail 303 Not Applicable 

For the selected sequences
All sequences(72) RefSeq(10) UniProt(6)
Polymorphisms RFLP(2) : SNPs within 2kb(77 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000301 Tetraspanin
InterPro IPR018503 Tetraspanin, conserved site
InterPro IPR008952 Tetraspanin, EC2 domain
InterPro IPR018499 Tetraspanin/Peripherin
Protein Ontology PR:000005170 CD37 molecule
References (Earliest) J:12638 Wright MD, et al., Gene structure, chromosomal localization, and protein sequence of mouse CD53 (Cd53): evidence that the transmembrane 4 superfamily arose by gene duplication. Int Immunol. 1993 Feb;5(2):209-16
(Latest) J:198155 Gartlan KH, et al., Tetraspanin CD37 contributes to the initiation of cellular immunity by promoting dendritic cell migration. Eur J Immunol. 2013 Apr;43(5):1208-19
All references(44)
Other
accession IDs
MGD-MRK-1850

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory