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Ccne1
Gene Detail
Symbol

Name
ID
Ccne1
cyclin E1
MGI:88316
Synonyms
CycE1, cyclin E
Feature Type
protein coding gene
Genetic Map
Chromosome 7
25.35 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr7:38097984-38107534 bp, - strand
From VEGA annotation of GRCm38

  9551 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:14452  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CCNE1
Protein SuperFamily: cyclin, A/B/D/E types
Gene Tree: Ccne1

Human
homologs
CCNE1, cyclin E1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 898
neXtProt AC: NX_P24864

Human Synonyms: CCNE, pCCNE1

Human Chr (Location): 19q12; chr19:29811898-29824312 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(25) : Gene trapped(18) Targeted(7)
Incidental mutations (data from APF , CvDC )
 
Mice homozygous for disruptions in this gene display no abnormal phenotype.
 
Interactions
Ccne1 interacts with 119 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (92 records)
Data Summary: Results (177)    Tissues (70)    Images (85)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 69
RNA in situ 39
Western blot 16
RT-PCR 53
cDNA source data(62)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase ccne1 ; ZFIN ccne1    NEW 
Molecular
reagents
All nucleic(71) Genomic(1) cDNA(63) Primer pair(6) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000022262 (Evidence)
Ensembl Gene Model ENSMUSG00000002068 (Evidence)
Entrez Gene 12447 (Evidence)
UniGene 16110
DFCI TC1579342, TC1726923
DoTS DT.55100395
NIA Mouse Gene Index U028449
Consensus CDS Project CCDS39914.1
International Mouse Phenotyping Consortium Status Ccne1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022262 VEGA Gene Model | MGI Sequence Detail 9551 C57BL/6J ±  kb
transcript OTTMUST00000053001 VEGA | MGI Sequence Detail 2000 Not Applicable 
polypeptide OTTMUSP00000025179 VEGA | MGI Sequence Detail 408 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(2) UniProt(4)
Polymorphisms
RFLP(1) : SNPs within 2kb(92 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004367 Cyclin, C-terminal domain
InterPro IPR013763 Cyclin-like
InterPro IPR006671 Cyclin, N-terminal
Protein Ontology PR:000005125 G1/S-specific cyclin-E1
References
(Earliest) J:18661 Damjanov I, et al., Molecular cloning and characterization of murine cyclin E. Biochem Biophys Res Commun. 1994 Jun 15;201(2):994-1000
(Latest) J:220960 Akiyama R, et al., Sall4-Gli3 system in early limb progenitors is essential for the development of limb skeletal elements. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5075-80
All references(159)
Other
accession IDs
MGD-MRK-1828, MGI:2142245

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory