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Ccnd3
Gene Detail
Symbol

Name
ID
Ccnd3
cyclin D3
MGI:88315
Synonyms
9230106B05Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 17
23.37 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr17:47505051-47599691 bp, + strand
From VEGA annotation of GRCm38

  94641 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20419  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

HCOP human homology predictions: CCND3
Protein SuperFamily: cyclin, A/B/D/E types
Gene Tree: Ccnd3

Human
homologs
CCND3, cyclin D3
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 896
neXtProt AC: NX_P30281

Human Chr (Location): 6p21; chr6:41934933-42048894 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(746) : Gene trapped(743) Targeted(3)
Incidental mutations (data from APF , CvDC )
 
Mice homozygous for a knock-out allele exhibit severe thymus hypoplasia, abnormal thymocyte development, and impaired expansion of immature T lymphocytes.
 
Interactions
Ccnd3 interacts with 130 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process cell cycle, cell division, ...
Component cyclin-dependent protein kinase holoenzyme complex, cytoplasm, ...
Function cyclin-dependent protein serine/threonine kinase activity, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (84 records)
Data Summary: Results (311)    Tissues (134)    Images (51)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 5
RNA in situ 161
Northern blot 51
Western blot 22
RT-PCR 72
cDNA source data(25)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: ZFIN ccnd3    NEW 
Molecular
reagents
All nucleic(32) cDNA(27) Primer pair(2) Other(3)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000044411 (Evidence)
Ensembl Gene Model ENSMUSG00000034165 (Evidence)
Entrez Gene 12445 (Evidence)
DFCI TC1573383, TC1605955, TC1617651, TC1683660, TC1688088, TC1701296
Consensus CDS Project CCDS28850.1
International Mouse Phenotyping Consortium Status Ccnd3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000044411 VEGA Gene Model | MGI Sequence Detail 94641 C57BL/6J ±  kb
transcript OTTMUST00000116929 VEGA | MGI Sequence Detail 2064 Not Applicable 
polypeptide OTTMUSP00000065327 VEGA | MGI Sequence Detail 292 Not Applicable 

For the selected sequences
All sequences(173) RefSeq(16) UniProt(14)
Polymorphisms
SNPs within 2kb(442 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004367 Cyclin, C-terminal domain
InterPro IPR015451 Cyclin D
InterPro IPR013763 Cyclin-like
InterPro IPR006671 Cyclin, N-terminal
Protein Ontology PR:000005123 G1/S-specific cyclin-D3
References
(Earliest) J:14776 Matsushime H, et al., Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle. Cell. 1991 May 17;65(4):701-13
(Latest) J:219894 Mattar P, et al., A conserved regulatory logic controls temporal identity in mouse neural progenitors. Neuron. 2015 Feb 4;85(3):497-504
All references(166)
Other
accession IDs
MGD-MRK-1827, MGI:1924959, MGI:2146781, MGI:2146960, MGI:2147051, MGI:2147125

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory