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Ccnb2
Gene Detail
Symbol

Name
ID
Ccnb2
cyclin B2
MGI:88311
Synonyms
CycB2
Feature Type
protein coding gene
Genetic Map
Chromosome 9
39.53 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:70407689-70421554 bp, - strand
From NCBI annotation of GRCm38

  13866 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74359  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CCNB2
Protein SuperFamily: cyclin, A/B/D/E types
Gene Tree: Ccnb2

Human
homologs
CCNB2, cyclin B2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 9133
neXtProt AC: NX_O95067

Human Synonyms: HsT17299

Human Chr (Location): 15q22.2; chr15:59105085-59125045 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(27) : Gene trapped(24) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Homozygous mutation of this gene results in reduced body weight and reduced litter size. Homozygous pups are underrepresented in litters from a heterozygous intercross.
 
Interactions
Ccnb2 interacts with 73 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cell cycle, cell division, ...
Component centrosome, membrane, ...
External Resources: FuncBase
Expression
Literature Summary: (14 records)
Data Summary: Results (133)    Tissues (32)    Images (36)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 78
Northern blot 15
RT-PCR 40
cDNA source data(90)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ccnb2 ; ZFIN ccnb2    NEW 
Molecular
reagents
All nucleic(93) cDNA(90) Primer pair(3)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000032218 (Evidence)
Entrez Gene 12442 (Evidence)
UniGene 22592
DFCI TC1576752
DoTS DT.535200
NIA Mouse Gene Index U031055
Consensus CDS Project CCDS23320.1
International Mouse Phenotyping Consortium Status Ccnb2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 12442 NCBI Gene Model | MGI Sequence Detail 13866 C57BL/6J ±  kb
transcript NM_007630 RefSeq | MGI Sequence Detail 1541 C57BL/6 
polypeptide P30276 UniProt | EBI | MGI Sequence Detail 398 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(48 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004367 Cyclin, C-terminal domain
InterPro IPR013763 Cyclin-like
InterPro IPR006671 Cyclin, N-terminal
Protein Ontology PR:000005118 G2/mitotic-specific cyclin-B2
Graphical View of Protein Domain Structure
References
(Earliest) J:1694 Hanley-Hyde J, et al., Expression of murine cyclin B1 mRNAs and genetic mapping of related genomic sequences. Genomics. 1992 Aug;13(4):1018-30
(Latest) J:211539 Chen Y, et al., Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21
All references(48)
Other
accession IDs
MGD-MRK-1823

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory