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Ccnb2 Gene Detail
Summary
  • Symbol
    Ccnb2
  • Name
    cyclin B2
  • Synonyms
    CycB2
  • Feature Type
    protein coding gene
  • IDs
    MGI:88311
    NCBI Gene: 12442
  • Gene Overview
    MyGene.info: CCNB2
Location & Maps
more
  • Sequence Map
    Chr9:70407689-70421554 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      13866 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 39.53 cM, cytoband D
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CCNB2, cyclin B2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CCNB2, cyclin B2
    Orthology source: HomoloGene
  • Synonyms
    HsT17299
  • Links
    NCBI Gene ID: 9133
    neXtProt AC: NX_O95067

  • Chr Location
    15q22.2; chr15:59105085-59125045 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    29
  • Chemically induced (other)
    1
  • Gene trapped
    24
  • Targeted
    4
  • Genomic Mutations
    1 involving Ccnb2
  • Incidental Mutations
Homozygous mutation of this gene results in reduced body weight and reduced litter size. Homozygous pups are underrepresented in litters from a heterozygous intercross.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 12442 NCBI Gene Model | MGI Sequence Detail 13866 C57BL/6J ±  kb
transcript NM_007630 RefSeq | MGI Sequence Detail 1541 C57BL/6  
polypeptide P30276 UniProt | EBI | MGI Sequence Detail 398 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    48 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 93
    cDNA 90
    Primer pair 3

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-1823
References
more
  • Summaries
    All 45
    Developmental Gene Expression 14
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:1694 Hanley-Hyde J, et al., Expression of murine cyclin B1 mRNAs and genetic mapping of related genomic sequences. Genomics. 1992 Aug;13(4):1018-30
  • Latest
    J:211539 Chen Y, et al., Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory