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Ccnb2
Gene Detail
 Symbol
Name
ID
Ccnb2
cyclin B2
MGI:88311
Synonyms CycB2
Feature Type protein coding gene
Genetic Map
Chromosome 9
39.53 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:70407689-70421554 bp, - strand
From NCBI annotation of GRCm38

  13866 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74359  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: cyclin, A/B/D/E types
Gene Tree: Ccnb2

Human
homologs
Human Homolog CCNB2, cyclin B2
NCBI Gene ID 9133
neXtProt AC  NX_O95067
Human Synonyms  HsT17299
Human Chr (Location)  15q22.2; chr15:59105085-59125045 (+)  GRCh38
Alleles
and
phenotypes
All alleles(27) : Gene trapped(24) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in reduced body weight and reduced litter size. Homozygous pups are underrepresented in litters from a heterozygous intercross.
 
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cell cycle, cell division, ...
Component centrosome, membrane, ...
Function protein kinase binding
External Resources: FuncBase
Expression
Literature Summary: (13 records)
Data Summary: Results (129)    Tissues (31)    Images (36)
Theiler Stages: 1, 2, 3, 4, 17, 20, 22, 23, 25, 28
Assay TypeResults
RNA in situ 78
Northern blot 15
RT-PCR 36
cDNA source data(90)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(92) cDNA(90) Primer pair(2)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000032218 (Evidence)
Entrez Gene12442 (Evidence)
UniGene22592
DFCITC1576752
DoTSDT.535200
NIA Mouse Gene IndexU031055
Consensus CDS ProjectCCDS23320.1
International Mouse Knockout Project StatusCcnb2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 12442 NCBI Gene Model | MGI Sequence Detail 13866 C57BL/6J ±  kb
transcript NM_007630 RefSeq | MGI Sequence Detail 1541 C57BL/6 
polypeptide P30276 UniProt | EBI | MGI Sequence Detail 398 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(48 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014400 Cyclin A/B/D/E
InterPro IPR004367 Cyclin, C-terminal domain
InterPro IPR013763 Cyclin-like
InterPro IPR006671 Cyclin, N-terminal
Protein Ontology PR:000005118 G2/mitotic-specific cyclin-B2
Graphical View of Protein Domain Structure
References (Earliest) J:1694 Hanley-Hyde J, et al., Expression of murine cyclin B1 mRNAs and genetic mapping of related genomic sequences. Genomics. 1992 Aug;13(4):1018-30
(Latest) J:196442 Gui L, et al., Hec1-dependent cyclin B2 stabilization regulates the G2-M transition and early prometaphase in mouse oocytes. Dev Cell. 2013 Apr 15;25(1):43-54
All references(48)
Other
accession IDs
MGD-MRK-1823

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory