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Cbr1 Gene Detail
Summary
  • Symbol
    Cbr1
  • Name
    carbonyl reductase 1
  • Synonyms
    CR
  • Feature Type
    protein coding gene
  • IDs
    MGI:88284
    NCBI Gene: 12408
  • Gene Overview
    MyGene.info: CBR1
Location & Maps
more
  • Sequence Map
    Chr16:93607837-93610505 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2669 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 54.53 cM
  • Mapping Data
    14 experiments
Homology
more
  • Human Ortholog
    CBR1, carbonyl reductase 1
  • Vertebrate Orthologs
    14
  • Human Ortholog
    CBR1, carbonyl reductase 1
    Orthology source: HomoloGene
  • Synonyms
    CBR, hCBR1, SDR21C1
  • Links
    NCBI Gene ID: 873
    neXtProt AC: NX_P16152

  • Chr Location
    21q22.13; chr21:36069924-36073177 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 37524
    1 human;1 mouse;3 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;3 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: CBR1
  • Gene Tree
Human Diseases
less
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from multigenic genotypes
    27 phenotype references
  • All Mutations and Alleles
    13
  • Gene trapped
    1
  • Targeted
    10
  • Transgenic
    2
  • Genomic Mutations
    8 involving Cbr1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019917 VEGA Gene Model | MGI Sequence Detail 2669 C57BL/6J ±  kb
transcript OTTMUST00000047490 VEGA | MGI Sequence Detail 1237 Not Applicable  
polypeptide OTTMUSP00000021476 VEGA | MGI Sequence Detail 277 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    76 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 89
    Genomic 4
    cDNA 82
    Primer pair 2
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-1787, MGI:2146635
References
more
  • Summaries
    All 43
    Developmental Gene Expression 3
    Diseases 3
    Gene Ontology 6
    Phenotypes 27
  • Earliest
    J:2142 Brookes S, et al., Localization of four human chromosome 21 genes--SOD1, ETS2, IFNAR, and CBR--to two different chromosomes in the marsupial species Macropus eugenii. Cytogenet Cell Genet. 1992;61(1):25-8
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory