About   Help   FAQ
Cbln2 Gene Detail
Summary
  • Symbol
    Cbln2
  • Name
    cerebellin 2 precursor protein
  • Synonyms
    6330593N19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:88282
    NCBI Gene: 12405
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:86711110-86718283 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 58.63 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    28 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88282
protein coding gene Chr18:86711052-86718285 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024614
protein coding gene Chr18:87934369-87941540 (+)
A/J MGP_AJ_G0024581
protein coding gene Chr18:84083230-84090403 (+)
AKR/J MGP_AKRJ_G0024552
protein coding gene Chr18:86576770-86583943 (+)
BALB/cJ MGP_BALBcJ_G0024579
protein coding gene Chr18:84294774-84301947 (+)
C3H/HeJ MGP_C3HHeJ_G0024348
protein coding gene Chr18:86682963-86690136 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025026
protein coding gene Chr18:90160488-90167661 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022457
protein coding gene Chr18:82600040-82607191 (+)
CAST/EiJ MGP_CASTEiJ_G0023821
protein coding gene Chr18:87079088-87086251 (+)
CBA/J MGP_CBAJ_G0024318
protein coding gene Chr18:93383367-93390540 (+)
DBA/2J MGP_DBA2J_G0024447
protein coding gene Chr18:83606966-83614139 (+)
FVB/NJ MGP_FVBNJ_G0024414
protein coding gene Chr18:82964519-82971692 (+)
LP/J MGP_LPJ_G0024532
protein coding gene Chr18:87763695-87770866 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024444
protein coding gene Chr18:94777123-94784296 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025075
protein coding gene Chr18:86820117-86827288 (+)
PWK/PhJ MGP_PWKPhJ_G0023566
protein coding gene Chr18:83983999-83991165 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023372
protein coding gene Chr18:86823161-86830343 (+)
WSB/EiJ MGP_WSBEiJ_G0023883
protein coding gene Chr18:86727802-86734972 (+)



Homology
more
  • Human Ortholog
    CBLN2, cerebellin 2 precursor
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CBLN2, cerebellin 2 precursor
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 147381
    neXtProt AC: NX_Q8IUK8
    UniProt: Q8IUK8

  • Chr Location
    18q22.3; chr18:72533720-72638485 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    93 phenotype references
No overt anatomical or neuroanatomical defects are observed in mice homozygous for deletion of this gene.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024647 Ensembl Gene Model | MGI Sequence Detail 7174 C57BL/6J ±  kb
transcript ENSMUST00000122079 Ensembl | MGI Sequence Detail 2549 Not Applicable  
polypeptide ENSMUSP00000113695 Ensembl | MGI Sequence Detail 224 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 22
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-1785, MGI:2443422
References
more
  • Summaries
    All 130
    Developmental Gene Expression 13
    Diseases 1
    Gene Ontology 4
    Phenotypes 93
  • Earliest
    J:21224 Kavety B, et al., Genomic structure and mapping of precerebellin and a precerebellin-related gene. Brain Res Mol Brain Res. 1994 Nov;27(1):152-6
  • Latest
    J:271149 Serra N, et al., The mTORC1 component RPTOR is required for maintenance of the foundational spermatogonial stem cell pool in mice. Biol Reprod. 2019 Feb 1;100(2):429-439

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/16/2019
MGI 6.13
The Jackson Laboratory