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Cbln1
Gene Detail
 Symbol
Name
ID
Cbln1
cerebellin 1 precursor protein
MGI:88281
Feature Type protein coding gene
Genetic Map
Chromosome 8
42.16 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr8:87468854-87472592 bp, - strand
From Ensembl annotation of GRCm38

  3739 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74520  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Cbln1

Human
homologs
Human Homolog CBLN1, cerebellin 1 precursor
NCBI Gene ID 869
neXtProt AC  NX_P23435
Human Chr (Location)  16q12.1; chr16:49277917-49281831 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in ataxia, impaired coordination, and abnormal Purkinje cell excitatory postsynaptic currents and innervation.
 
Interactions
Cbln1 interacts with 177 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process cerebellar granule cell differentiation, heterophilic cell-cell adhesion, ...
Component cell, cell junction, ...
Function protein binding, protein homodimerization activity
External Resources: FuncBase
Expression
Literature Summary: (20 records)
Data Summary: Results (146)    Tissues (80)    Images (35)
Theiler Stages: 18, 19, 20, 21, 22, 23, 24, 26, 27, 28
Assay TypeResults
RNA in situ 88
RT-PCR 58
cDNA source data(27)
External Resources: GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(43) Genomic(6) cDNA(29) Primer pair(7) Other(1)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000031654 (Evidence)
Entrez Gene12404 (Evidence)
UniGene4880
DFCITC1581527, TC1623561
DoTSDT.110871019, DT.40177046, DT.91305097, DT.94346630
NIA Mouse Gene IndexU030071
Consensus CDS ProjectCCDS22506.1
International Mouse Knockout Project StatusCbln1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031654 Ensembl Gene Model | MGI Sequence Detail 3739 C57BL/6J ±  kb
transcript ENSMUST00000034076 Ensembl | MGI Sequence Detail 2334 Not Applicable 
polypeptide ENSMUSP00000034076 Ensembl | MGI Sequence Detail 193 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(4)
Polymorphisms RFLP(1) : SNPs within 2kb(39 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001073 Complement C1q protein
InterPro IPR008983 Tumour necrosis factor-like domain
Protein Ontology PR:000005074 cerebellin-1
References (Earliest) J:21224 Kavety B, et al., Genomic structure and mapping of precerebellin and a precerebellin-related gene. Brain Res Mol Brain Res. 1994 Nov;27(1):152-6
(Latest) J:196989 Ito-Ishida A, et al., Presynaptically released Cbln1 induces dynamic axonal structural changes by interacting with GluD2 during cerebellar synapse formation. Neuron. 2012 Nov 8;76(3):549-64
All references(61)
Other
accession IDs
MGD-MRK-1784, MGI:2142504

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory