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Cbln1
Gene Detail
Symbol

Name
ID
Cbln1
cerebellin 1 precursor protein
MGI:88281
Feature Type
protein coding gene
Genetic Map
Chromosome 8
42.16 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr8:87468854-87472592 bp, - strand
From Ensembl annotation of GRCm38

  3739 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74520  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: CBLN1
Gene Tree: Cbln1

Human
homologs
CBLN1, cerebellin 1 precursor
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 869
neXtProt AC: NX_P23435

Human Chr (Location): 16q12.1; chr16:49277917-49281831 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in ataxia, impaired coordination, and abnormal Purkinje cell excitatory postsynaptic currents and innervation.
 
Interactions
Cbln1 interacts with 177 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (22 records)
Data Summary: Results (144)    Tissues (85)    Images (35)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 86
RT-PCR 58
cDNA source data(27)
Other mouse links: GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase cbln1    NEW 
Molecular
reagents
All nucleic(43) Genomic(6) cDNA(29) Primer pair(7) Other(1)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000031654 (Evidence)
Entrez Gene 12404 (Evidence)
UniGene 4880
DFCI TC1581527, TC1623561
DoTS DT.110871019, DT.40177046, DT.91305097, DT.94346630
NIA Mouse Gene Index U030071
Consensus CDS Project CCDS22506.1
International Mouse Phenotyping Consortium Status Cbln1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031654 Ensembl Gene Model | MGI Sequence Detail 3739 C57BL/6J ±  kb
transcript ENSMUST00000034076 Ensembl | MGI Sequence Detail 2334 Not Applicable 
polypeptide ENSMUSP00000034076 Ensembl | MGI Sequence Detail 193 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(4)
Polymorphisms
RFLP(1) : SNPs within 2kb(39 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001073 C1q domain
InterPro IPR008983 Tumour necrosis factor-like domain
Protein Ontology PR:000005074 cerebellin-1
References
(Earliest) J:21224 Kavety B, et al., Genomic structure and mapping of precerebellin and a precerebellin-related gene. Brain Res Mol Brain Res. 1994 Nov;27(1):152-6
(Latest) J:219786 Naillat F, et al., Identification of the genes regulated by Wnt-4, a critical signal for commitment of the ovary. Exp Cell Res. 2015 Mar 15;332(2):163-78
All references(61)
Other
accession IDs
MGD-MRK-1784, MGI:2142504

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory