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Camk2g
Gene Detail
Symbol

Name
ID
Camk2g
calcium/calmodulin-dependent protein kinase II gamma
MGI:88259
Synonyms
5930429P18Rik, Ca2+/calmodulin-dependent protein kinase II, Camkg, CaMK II
Feature Type
protein coding gene
Genetic Map
Chromosome 14
11.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:20734875-20794088 bp, - strand
From Ensembl annotation of GRCm38

  59214 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:15596  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: calcium/calmodulin-dependent protein kinase II
Gene Tree: Camk2g

Human
homologs
Human Homolog CAMK2G, calcium/calmodulin-dependent protein kinase II gamma
NCBI Gene ID 818
neXtProt AC  NX_Q13555
Human Synonyms  CAMK, CAMKG, CAMK-II
Human Chr (Location)  10q22; chr10:73812501-73874591 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(2) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit female infertility and decreased sensitivity of macrophages to ER stress-induced apoptosis.
 
Interactions
Camk2g interacts with 306 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (28 annotations)
Process calcium ion transport, cell differentiation, ...
Component membrane, neuronal postsynaptic density, ...
Function ATP binding, calmodulin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (11 records)
Data Summary: Results (232)    Tissues (148)    Images (52)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 222
RT-PCR 10
cDNA source data(16)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(19) Genomic(1) cDNA(16) Primer pair(2)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000021820 (Evidence)
Entrez Gene12325 (Evidence)
DFCITC1640503, TC1729474, TC1592070, TC1589823, TC1572807
DoTSDT.532494, DT.94275780, DT.532555, DT.101390072, DT.101235364, DT.101337254, DT.101143928
NIA Mouse Gene IndexU035289
EC2.7.11.17
Consensus CDS ProjectCCDS26855.1, CCDS26856.1, CCDS26857.1
International Mouse Knockout Project StatusCamk2g
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021820 Ensembl Gene Model | MGI Sequence Detail 59214 C57BL/6J ±  kb
transcript ENSMUST00000071816 Ensembl | MGI Sequence Detail 3703 Not Applicable 
polypeptide ENSMUSP00000071720 Ensembl | MGI Sequence Detail 529 Not Applicable 

For the selected sequences
All sequences(80) RefSeq(34) UniProt(5)
Polymorphisms
SNPs within 2kb(126 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020636 Calcium/calmodulin-dependent/calcium-dependent protein kinase
InterPro IPR013543 Calcium/calmodulin-dependent protein kinase II, association-domain
InterPro IPR017441 Protein kinase, ATP binding site
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR011009 Protein kinase-like domain
InterPro IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain
InterPro IPR008271 Serine/threonine-protein kinase, active site
Protein Ontology PR:000003202 calcium/calmodulin-dependent protein kinase type II subunit gamma
References
(Earliest) J:16757 Li X, et al., Localization of the CAMKG gene encoding gamma isoforms of multifunctional calcium/calmodulin-dependent protein kinase (CaM kinase) to human chromosome 10 band q22 and mouse chromosome 14. Cytogenet Cell Genet. 1994;66(2):113-6
(Latest) J:206150 Ozcan L, et al., Activation of calcium/calmodulin-dependent protein kinase II in obesity mediates suppression of hepatic insulin signaling. Cell Metab. 2013 Dec 3;18(6):803-15
All references(57)
Other
accession IDs
MGD-MRK-1746, MGI:2442091

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory