About   Help   FAQ
Calm1 Gene Detail
Summary
  • Symbol
    Calm1
  • Name
    calmodulin 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:88251
    NCBI Gene: 12313
  • Gene Overview
    MyGene.info: CALM1
  • Alliance
  • Transcription Start Sites
    16 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:100199435-100209814 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 50.43 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    73 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88251
protein coding gene Chr12:100199435-100209824 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020017
protein coding gene Chr12:101667549-101677917 (+)
A/J MGP_AJ_G0019972
protein coding gene Chr12:97844543-97854913 (+)
AKR/J MGP_AKRJ_G0019948
protein coding gene Chr12:100494170-100504546 (+)
BALB/cJ MGP_BALBcJ_G0019958
protein coding gene Chr12:98189088-98199456 (+)
C3H/HeJ MGP_C3HHeJ_G0019760
protein coding gene Chr12:101031168-101041538 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020407
protein coding gene Chr12:104806234-104816595 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018021
protein coding gene Chr12:94817343-94827713 (+)
CAST/EiJ MGP_CASTEiJ_G0019306
protein coding gene Chr12:96144738-96155103 (+)
CBA/J MGP_CBAJ_G0019732
protein coding gene Chr12:108693820-108704190 (+)
DBA/2J MGP_DBA2J_G0019843
protein coding gene Chr12:97280136-97291635 (+)
FVB/NJ MGP_FVBNJ_G0019832
protein coding gene Chr12:96000448-96010849 (+)
LP/J MGP_LPJ_G0019919
protein coding gene Chr12:101503973-101514341 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019874
protein coding gene Chr12:112285352-112295720 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020436
protein coding gene Chr12:100062238-100072606 (+)
PWK/PhJ MGP_PWKPhJ_G0019070
protein coding gene Chr12:91914960-91925949 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018866
protein coding gene Chr12:94244920-94257335 (+)
WSB/EiJ MGP_WSBEiJ_G0019360
protein coding gene Chr12:100917020-100928654 (+)



Homology
more
  • Human Ortholog
    CALM1, calmodulin 1
  • Vertebrate Orthologs
    23
  • Human Ortholog
    CALM1, calmodulin 1
    Orthology source: HGNC
  • Synonyms
    CALML2, caM, CAM2, CAM3, CAMB, CAMC, CAMI, CAMIII, CPVT4, DD132, LQT14, PHKD
  • Links
    NCBI Gene ID: 801
    neXtProt AC: NX_P0DP23, NX_P0DP24, NX_P0DP25
    UniProt: P0DP23

  • Chr Location
    14q32.11; chr14:90396983-90408275 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    2 with human CALM1 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    37 phenotypes from multigenic genotypes
    61 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000001175 Ensembl Gene Model | MGI Sequence Detail 10380 C57BL/6J ±  kb
    transcript ENSMUST00000238462 Ensembl | MGI Sequence Detail 594 Not Applicable  
    polypeptide ENSMUSP00000158788 Ensembl | MGI Sequence Detail 197 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    Molecular
    Reagents
    less
    • All nucleic 60
      cDNA 54
      Primer pair 4
      Other 2

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGD-MRK-1734, MGI:2144778, MGI:2144797, MGI:2144834, MGI:2144926
    References
    more
    • Summaries
      All 141
      Developmental Gene Expression 13
      Diseases 2
      Gene Ontology 6
      Phenotypes 61
    • Earliest
      J:9357 Kluxen FW, et al., Opposite regulation of the mRNAs for parvalbumin and p19/6.8 in myotonic mouse muscle. Eur J Biochem. 1988 Sep 1;176(1):153-8
    • Latest
      J:272366 Marimoutou M, et al., Oxidation of Methionine 77 in Calmodulin Alters Mouse Growth and Behavior. Antioxidants (Basel). 2018 Oct 13;7(10)

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    10/08/2019
    MGI 6.14
    The Jackson Laboratory