C8g
Gene Detail

Symbol Name ID

C8g complement component 8, gamma polypeptide MGI:88237

Synonyms

1700013L23Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 2

17.31 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(6)

Sequence Map

Chr2:25498651-25501719 bp, - strand From VEGA annotation of GRCm38   3069 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:505  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: complement component C8, gamma chain
Gene Tree: C8g

Human homologs

Human Homolog		C8G, complement component 8, gamma polypeptide
NCBI Gene ID		733
neXtProt AC		NX_P07360
Human Synonyms		C8C
Human Chr (Location)		9q34.3; chr9:139839698-139841426 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	complement activation, alternative pathway, complement activation, classical pathway, ...
Component	extracellular region, extracellular space, ...
Function	complement binding, protein complex binding, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (24)    Tissues (1)    Images (24)
Theiler Stages: 23

Assay Type	Results
RNA in situ	24

cDNA source data(55)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(58) cDNA(57) Other(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000012120 (Evidence)
Ensembl Gene Model	ENSMUSG00000015083 (Evidence)
Entrez Gene	69379 (Evidence)
UniGene	24596
DFCI	TC1581685
DoTS	DT.492128, DT.91337473
NIA Mouse Gene Index	U022395
Consensus CDS Project	CCDS15777.1
International Mouse Knockout Project Status	C8g

Sequences

Length	Strain/Species
genomic	OTTMUSG00000012120	VEGA Gene Model | MGI Sequence Detail	3069	C57BL/6J
transcript	OTTMUST00000028927	VEGA | MGI Sequence Detail	1150	Not Applicable
polypeptide	OTTMUSP00000013072	VEGA | MGI Sequence Detail	202	Not Applicable

All sequences(36) RefSeq(4) UniProt(2)

Polymorphisms

RFLP(3) : SNPs(30 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002968	Alpha-1-microglobulin
InterPro	IPR012674	Calycin
InterPro	IPR011038	Calycin-like
InterPro	IPR002345	Lipocalin
InterPro	IPR022272	Lipocalin conserved site
InterPro	IPR000566	Lipocalin/cytosolic fatty-acid binding protein domain
Protein Ontology	PR:000004910	complement component C8 gamma chain

References

(Earliest) J:11178 Spies T, et al., Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter [see comments]. Nature. 1991 May 23;351(6324):323-4
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)

Other accession IDs

MGD-MRK-1715, MGI:1916629