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Bmyc
Gene Detail
Symbol

Name
ID
Bmyc
brain expressed myelocytomatosis oncogene
MGI:88184
Synonyms
2900002K07Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 2
17.82 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr2:25706739-25707721 bp, + strand
From VEGA annotation of GRCm38

  983 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11343  Vertebrate Homology Class
1 mouse; 1 rat

Gene Tree: Bmyc

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
 
Mice homozygous for a knock-out allele exhibit partial lethality, reduced body weight in male mice and abnormal male reproductive system morphology.
 
Interactions
Bmyc interacts with 66 markers (Mir7-1, Mir34b, Mir34c, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process regulation of transcription, DNA-templated
Component nucleus, spindle
Function protein binding, sequence-specific DNA binding transcription factor activity
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (63)    Tissues (53)    Images (11)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 53
RT-PCR 8
RNase protection 2
cDNA source data(43)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(49) Genomic(3) cDNA(43) Primer pair(1) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000012633 (Evidence)
Ensembl Gene ModelENSMUSG00000049086 (Evidence)
Entrez Gene107771 (Evidence)
UniGene330057
DFCITC1579896
DoTSDT.110650766, DT.492608
Consensus CDS ProjectCCDS15789.1
International Mouse Knockout Project StatusBmyc
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012633 VEGA Gene Model | MGI Sequence Detail 983 C57BL/6J ±  kb
transcript OTTMUST00000030063 VEGA | MGI Sequence Detail 983 Not Applicable 
polypeptide OTTMUSP00000013515 VEGA | MGI Sequence Detail 170 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(13 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002418 Transcription regulator Myc
InterPro IPR012682 Transcription regulator Myc, N-terminal
Protein Ontology PR:000010935 protein B-Myc
References
(Earliest) J:4488 Ingvarsson S, et al., Chromosome localization and expression pattern of Lmyc and Bmyc in murine embryonal carcinoma cells. Oncogene. 1988 Dec;3(6):679-85
(Latest) J:191587 Turunen HT, et al., Loss of Bmyc results in increased apoptosis associated with upregulation of Myc expression in juvenile murine testis. Reproduction. 2012 Oct;144(4):495-503
All references(40)
Other
accession IDs
MGD-MRK-1606, MGI:1914503, MGI:2139289

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory