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Bmyc Gene Detail
Summary
  • Symbol
    Bmyc
  • Name
    brain expressed myelocytomatosis oncogene
  • Synonyms
    2900002K07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:88184
    NCBI Gene: 107771
Location & Maps
more
Homology
less
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    1
  • Targeted
    1
Mice homozygous for a knock-out allele exhibit partial lethality, reduced body weight in male mice and abnormal male reproductive system morphology.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012633 VEGA Gene Model | MGI Sequence Detail 983 C57BL/6J ±  kb
transcript OTTMUST00000030063 VEGA | MGI Sequence Detail 983 Not Applicable  
polypeptide OTTMUSP00000013515 VEGA | MGI Sequence Detail 170 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    13 from dbSNP Build 137
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000010935 protein B-Myc
  • InterPro Domains
    IPR002418 Transcription regulator Myc
    IPR012682 Transcription regulator Myc, N-terminal
Molecular
Reagents
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  • All nucleic 49
    Genomic 3
    cDNA 43
    Primer pair 1
    Other 2

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-1606, MGI:1914503, MGI:2139289
References
more
  • Summaries
    All 35
    Developmental Gene Expression 7
    Gene Ontology 4
    Phenotypes 1
  • Earliest
    J:4488 Ingvarsson S, et al., Chromosome localization and expression pattern of Lmyc and Bmyc in murine embryonal carcinoma cells. Oncogene. 1988 Dec;3(6):679-85
  • Latest
    J:191587 Turunen HT, et al., Loss of Bmyc results in increased apoptosis associated with upregulation of Myc expression in juvenile murine testis. Reproduction. 2012 Oct;144(4):495-503

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory