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Blvra
Gene Detail
 Symbol
Name
ID
Blvra
biliverdin reductase A
MGI:88170
Synonyms 0610006A11Rik, 2500001N03Rik, Blvr
Feature Type protein coding gene
Genetic Map
Chromosome 2
61.76 cM, cytoband F3
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr2:127070665-127097084 bp, + strand
From VEGA annotation of GRCm38

  26420 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:572  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: biliverdin reductase A
Gene Tree: Blvra

Human
homologs
Human Homolog BLVRA, biliverdin reductase A
NCBI Gene ID 644
neXtProt AC  NX_P53004
Human Synonyms  BLVR, BVR, BVRA
Human Chr (Location)  7p13; chr7:43758673-43807342 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human BLVRA
Alleles
and
phenotypes
All alleles(30) : Gene trapped(28) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
This locus controls electrophoretic mobility of biliverdin reductase. The a allele determines a slowly migrating band in C3H/He, C57BL/H and 101/H; the b allele determines a fast band in BALB/c, CBA/Ca, TFH/H and SM/J. Heterozygotes have both parental bands.
 
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process heme catabolic process, oxidation-reduction process
Component cytoplasm, extracellular vesicular exosome
Function biliverdin reductase activity, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (8)    Tissues (4)   
Theiler Stages: 22, 28
Assay TypeResults
Immunohistochemistry 8
cDNA source data(41)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(42) cDNA(42)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000016013 (Evidence)
Ensembl Gene ModelENSMUSG00000001999 (Evidence)
Entrez Gene109778 (Evidence)
UniGene22028
DFCITC1579026
DoTSDT.488039, DT.101387958, DT.94132127
NIA Mouse Gene IndexU002428
EC1.3.1.24
Consensus CDS ProjectCCDS16692.1
International Mouse Knockout Project StatusBlvra
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016013 VEGA Gene Model | MGI Sequence Detail 26420 C57BL/6J ±  kb
transcript OTTMUST00000038153 VEGA | MGI Sequence Detail 1160 Not Applicable 
polypeptide OTTMUSP00000017108 VEGA | MGI Sequence Detail 295 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(12) UniProt(5)
Polymorphisms SNPs within 2kb(193 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017094 Biliverdin reductase A
InterPro IPR015249 Biliverdin reductase, catalytic
InterPro IPR016040 NAD(P)-binding domain
InterPro IPR000683 Oxidoreductase, N-terminal
Protein Ontology PR:000004765 biliverdin reductase A
References (Earliest) J:13963 von Deimling OH, et al., Linkage of biliverdin reductase, Blvr. Mouse News Lett. 1984;70:81
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(41)
Other
accession IDs
MGD-MRK-1581, MGI:1915580, MGI:1917355

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory