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Atp6v0c
Gene Detail
Symbol

Name
ID
Atp6v0c
ATPase, H+ transporting, lysosomal V0 subunit C
MGI:88116
Synonyms
Atp6c2, Atp6l, Atpl, Atpl-rs1, H(+)-ATPase (mvp), PL16, proteolipid
Feature Type
protein coding gene
Genetic Map
Chromosome 17
12.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr17:24163866-24169702 bp, - strand
From VEGA annotation of GRCm38

  5837 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68199  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: ATP6V0C
Gene Tree: Atp6v0c

Human
homologs
ATP6V0C, ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 527
neXtProt AC: NX_P27449

Human Synonyms: ATP6C, ATP6L, ATPL, VATL, Vma3, VPPC

Human Chr (Location): 16p13.3; chr16:2513726-2520223 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(8) Targeted(1)
 
Homozygous mutation of this gene results in embryonic lethality.
 
Interactions
Atp6v0c interacts with 111 markers (Mir1a-1, Mir1a-2, Mir26a-2, ...)
Expression
Literature Summary: (8 records)
Data Summary: Results (299)    Tissues (150)    Images (50)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 287
Northern blot 8
RT-PCR 4
cDNA source data(26)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase atp6v0c ; ZFIN atp6v0ca, atp6v0cb    NEW 
Molecular
reagents
All nucleic(31) cDNA(28) Primer pair(3)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000023843 (Evidence)
Ensembl Gene Model ENSMUSG00000024121 (Evidence)
Entrez Gene 11984 (Evidence)
DoTS DT.101221474, DT.101351961, DT.101402573, DT.110471148, DT.537511, DT.91434975
Consensus CDS Project CCDS28476.1
International Mouse Phenotyping Consortium Status Atp6v0c
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023843 VEGA Gene Model | MGI Sequence Detail 5837 C57BL/6J ±  kb
transcript OTTMUST00000058234 VEGA | MGI Sequence Detail 1183 Not Applicable 
polypeptide OTTMUSP00000028185 VEGA | MGI Sequence Detail 155 Not Applicable 

For the selected sequences
All sequences(71) RefSeq(2) UniProt(7)
Polymorphisms
RFLP(2) : SNPs within 2kb(81 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000245 V-ATPase proteolipid subunit
InterPro IPR011555 V-ATPase proteolipid subunit C, eukaryotic
InterPro IPR002379 V-ATPase proteolipid subunit C-like domain
Protein Ontology PR:000004475 V-type proton ATPase 16 kDa proteolipid subunit
References
(Earliest) J:20078 Hanada H, et al., Molecular cloning of cDNA encoding the 16 KDa subunit of vacuolar H(+)-ATPase from mouse cerebellum. Biochem Biophys Res Commun. 1991 May 15;176(3):1062-7
(Latest) J:213512 Werber M, et al., The tissue-specific transcriptomic landscape of the mid-gestational mouse embryo. Development. 2014 Jun;141(11):2325-30
All references(47)
Other
accession IDs
MGD-MRK-1476, MGD-MRK-36190, MGD-MRK-36468, MGI:107616

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory