Most homozygous null mutants may die by 6 months of age with highly abnormal kidney morphology and kidney tubule obstructions depending on the genetic background. Mice have elevated urinary 2,8-hydroxyadenine and crystalline deposits in kidney. Severity varies by genetic background.
|Ensembl Gene Model||ENSMUSG00000006589 (Evidence)|
|Entrez Gene||11821 (Evidence)|
|DoTS||DT.101370164, DT.102551876, DT.103600358, DT.110857264, DT.536302|
|NIA Mouse Gene Index||U030359|
|Consensus CDS Project||CCDS40503.1|
|International Mouse Phenotyping Consortium Status||Aprt|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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