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Apod
Gene Detail
Symbol

Name
ID
Apod
apolipoprotein D
MGI:88056
Feature Type
protein coding gene
Genetic Map
Chromosome 16
21.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(11)
Sequence Map
Chr16:31296192-31314808 bp, - strand
From VEGA annotation of GRCm38

  18617 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1246  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

HCOP human homology predictions: APOD
Protein SuperFamily: lipocalin, ApoD type
Gene Tree: Apod

Human
homologs
APOD, apolipoprotein D
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 347
neXtProt AC: NX_P05090

Human Chr (Location): 3q29; chr3:195568702-195584205 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(21) : Gene trapped(17) Targeted(4)
 
Mice homozygous for one null allele display increased sensitivity to reactive oxygen species, impaired motor and spatial learning, and decreased vertical and horizontal activity.
 
Interactions
Apod interacts with 122 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (31 annotations)
Process glucose metabolic process, lipid metabolic process, ...
Component cytoplasm, cytosolic ribosome, ...
Function cholesterol binding, lipid binding, ...
External Resources: FuncBase
Expression
Literature Summary: (13 records)
Data Summary: Results (292)    Tissues (83)    Images (74)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 292
cDNA source data(17)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: GEISHA APOD    NEW 
Molecular
reagents
All nucleic(22) Genomic(3) cDNA(19)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000025876 (Evidence)
Ensembl Gene Model ENSMUSG00000022548 (Evidence)
Entrez Gene 11815 (Evidence)
DFCI TC1572356
DoTS DT.101169604, DT.494666
NIA Mouse Gene Index U036966
Consensus CDS Project CCDS28105.1
International Mouse Phenotyping Consortium Status Apod
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025876 VEGA Gene Model | MGI Sequence Detail 18617 C57BL/6J ±  kb
transcript OTTMUST00000063759 VEGA | MGI Sequence Detail 2074 Not Applicable 
polypeptide OTTMUSP00000031576 VEGA | MGI Sequence Detail 189 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(6) UniProt(1)
Polymorphisms
RFLP(3) : SNPs within 2kb(217 from dbSNP Build 137)    SNPs within 2kb including multiple locations(221)
Protein-related
information
ResourceIDDescription
InterPro IPR002969 Apolipoprotein D
InterPro IPR026222 Apolipoprotein D, vertebrates
InterPro IPR012674 Calycin
InterPro IPR011038 Calycin-like
InterPro IPR002345 Lipocalin
InterPro IPR022271 Lipocalin, ApoD type
InterPro IPR022272 Lipocalin conserved site
InterPro IPR000566 Lipocalin/cytosolic fatty-acid binding protein domain
Protein Ontology PR:000004154 apolipoprotein D
References
(Earliest) J:2968 Warden CH, et al., Localization of the gene for apolipoprotein D on mouse chromosome 16. Genomics. 1992 Apr;12(4):851-2
(Latest) J:211808 Carpanini SM, et al., A novel mouse model of Warburg Micro syndrome reveals roles for RAB18 in eye development and organisation of the neuronal cytoskeleton. Dis Model Mech. 2014 Jun;7(6):711-22
All references(61)
Other
accession IDs
MGD-MRK-1375

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory