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Ang Gene Detail
Summary
  • Symbol
    Ang
  • Name
    angiogenin, ribonuclease, RNase A family, 5
  • Synonyms
    Ang1, Rnase5a
  • Feature Type
    protein coding gene
  • IDs
    MGI:88022
    NCBI Gene: 11727
  • Gene Overview
    MyGene.info: ANG
Location & Maps
more
  • Sequence Map
    Chr14:51091077-51102007 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10931 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ANG, angiogenin
  • Vertebrate Orthologs
    5
  • Human Ortholog
    ANG, angiogenin
    Orthology source: HomoloGene
  • Synonyms
    ALS9, HEL168, RAA1, RNASE4, RNASE5
  • Links
    NCBI Gene ID: 283
    neXtProt AC: NX_P03950

  • Chr Location
    14q11.1-q11.2; chr14:20684177-20694186 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human ANG associations

Human Disease Mouse Models
       Amyotrophic Lateral Sclerosis 9; ALS9   OMIM: 611895
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Targeted
    4
  • Genomic Mutations
    1 involving Ang
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000072115 Ensembl Gene Model | MGI Sequence Detail 10931 C57BL/6J ±  kb
transcript ENSMUST00000171688 Ensembl | MGI Sequence Detail 799 Not Applicable  
polypeptide ENSMUSP00000132084 Ensembl | MGI Sequence Detail 145 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    216 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    Genomic 2
    cDNA 5
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-1320, MGI:2145626
References
more
  • Summaries
    All 54
    Developmental Gene Expression 6
    Gene Ontology 9
    Phenotypes 5
  • Earliest
    J:10791 Bond MD, et al., Isolation and sequencing of mouse angiogenin DNA. Biochem Biophys Res Commun. 1990 Sep 28;171(3):988-95
  • Latest
    J:224939 Hare LM, et al., Heterozygous expression of the oncogenic Pik3ca(H1047R) mutation during murine development results in fatal embryonic and extraembryonic defects. Dev Biol. 2015 Aug 1;404(1):14-26

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory