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Ang Gene Detail
Summary
  • Symbol
    Ang
  • Name
    angiogenin, ribonuclease, RNase A family, 5
  • Synonyms
    Ang1, Rnase5a
  • Feature Type
    protein coding gene
  • IDs
    MGI:88022
    NCBI Gene: 11727
  • Gene Overview
    MyGene.info: ANG
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:51091150-51102009 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 26.37 cM, cytoband B-C1
  • Mapping Data
    9 experiments
Strain
Comparison
more
  • SNPs within 2kb
    216 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88022
protein coding gene Chr14:51091077-51102009 (.)
129S1/SvImJ MGP_129S1SvImJ_G0021271
protein coding gene Chr14:45054548-45069511 (+)
A/J MGP_AJ_G0021225
protein coding gene Chr14:43704153-43715912 (+)
AKR/J MGP_AKRJ_G0021201
protein coding gene Chr14:45353901-45364930 (+)
BALB/cJ MGP_BALBcJ_G0021228
protein coding gene Chr14:43824801-43840884 (+)
C3H/HeJ MGP_C3HHeJ_G0021010
protein coding gene Chr14:45175392-45186239 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021665
protein coding gene Chr14:46906077-46918559 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0020534
protein coding gene Chr14:42241074-42251873 (+)
CBA/J MGP_CBAJ_G0020977
protein coding gene Chr14:48364052-48374885 (+)
DBA/2J MGP_DBA2J_G0021101
protein coding gene Chr14:43598590-43609421 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0021169
protein coding gene Chr14:45348179-45360336 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0021694
protein coding gene Chr14:44838691-44849601 (+)
PWK/PhJ MGP_PWKPhJ_G0020284
protein coding gene Chr14:40499254-40741035 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020109
protein coding gene Chr14:41007490-41246378 (+)
WSB/EiJ MGP_WSBEiJ_G0020587
protein coding gene Chr14:45036910-45048908 (+)



Homology
more
  • Human Ortholog
    ANG, angiogenin
  • Vertebrate Orthologs
    5
  • Human Ortholog
    ANG, angiogenin
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ALS9, HEL168, RAA1, RNASE4, RNASE5
  • Links
    NCBI Gene ID: 283
    neXtProt AC: NX_P03950
    UniProt: P03950

  • Chr Location
    14q11.2; chr14:20684177-20694186 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human ANG associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000072115 Ensembl Gene Model | MGI Sequence Detail 10860 C57BL/6J ±  kb
transcript ENSMUST00000171688 Ensembl | MGI Sequence Detail 728 Not Applicable  
polypeptide ENSMUSP00000132084 Ensembl | MGI Sequence Detail 145 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    Genomic 2
    cDNA 6
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-1320, MGI:2145626
References
more
  • Summaries
    All 67
    Developmental Gene Expression 8
    Gene Ontology 9
    Phenotypes 7
  • Earliest
    J:10791 Bond MD, et al., Isolation and sequencing of mouse angiogenin DNA. Biochem Biophys Res Commun. 1990 Sep 28;171(3):988-95
  • Latest
    J:258670 Mahany EB, et al., Obesity and High-Fat Diet Induce Distinct Changes in Placental Gene Expression and Pregnancy Outcome. Endocrinology. 2018 Apr 1;159(4):1718-1733

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory