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Amy2a5 Gene Detail
Summary
  • Symbol
    Amy2a5
  • Name
    amylase 2a5
  • Synonyms
    Amy2, Amy-2, mAmy2-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:88020
    NCBI Gene: 109959
  • Member of
    Amy cluster
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr3:113249178-113258699 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 49.35 cM
  • Mapping Data
    38 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3 from dbSNP Build 142
  • Strain Annotations
    4
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88020
protein coding gene Chr3:113247178-113258837 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027798
protein coding gene Chr3:115093533-115094378 (-)
A/J no annotation
AKR/J MGP_AKRJ_G0027722
protein coding gene Chr3:114331977-114351419 (-)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0028213
protein coding gene Chr3:119231412-119529658 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    AMY1A, amylase, alpha 1A (salivary)
  • Vertebrate Orthologs
    10
  • Human Ortholog
    AMY1A, amylase, alpha 1A (salivary)
    Orthology source: HGNC
  • Synonyms
    AMY1
  • Links
    NCBI Gene ID: 276
    neXtProt AC: NX_P04745
    UniProt: P04745

  • Chr Location
    1p21.1; chr1:103655519-103664551 (+)  GRCh38.p7

  • Human Ortholog
    AMY1B, amylase, alpha 1B (salivary)
    Orthology source: HGNC
  • Synonyms
    AMY1
  • Links
    NCBI Gene ID: 277
    neXtProt AC: NX_P04745
    UniProt: P04745

  • Chr Location
    1p21.1; chr1:103687415-103696452 (-)  GRCh38.p7

  • Human Ortholog
    AMY1C, amylase, alpha 1C (salivary)
    Orthology source: HGNC
  • Synonyms
    AMY1
  • Links
    NCBI Gene ID: 278
    neXtProt AC: NX_P04745
    UniProt: P04745

  • Chr Location
    1p21.1; chr1:103745430-103758692 (+)  GRCh38.p7

  • Human Ortholog
    AMY2A, amylase, alpha 2A (pancreatic)
    Orthology source: HGNC
  • Synonyms
    AMY2, PA
  • Links
    NCBI Gene ID: 279
    neXtProt AC: NX_P04746
    UniProt: P04746

  • Chr Location
    1p21.1; chr1:103617332-103625780 (+)  GRCh38.p7

  • Human Ortholog
    AMY2B, amylase, alpha 2B (pancreatic)
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AMY2, AMY3, HXA
  • Links
    NCBI Gene ID: 280
    neXtProt AC: NX_P19961
    UniProt: P19961

  • Chr Location
    1p21.1; chr1:103554644-103579534 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Amy2a5
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 109959 NCBI Gene Model | MGI Sequence Detail 9522 C57BL/6J ±  kb
transcript NM_001042711 RefSeq | MGI Sequence Detail 1577 C57BL/6  
polypeptide NP_001036176 RefSeq | MGI Sequence Detail 508 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 19
    Genomic 4
    cDNA 14
    Other 1

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-1314, MGD-MRK-1316
References
more
  • Summaries
    All 103
    Diseases 1
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:12977 Sick K, et al., Genetics of amylase isozymes in the mouse. Hereditas. 1964;51:291-296
  • Latest
    J:119468 Kedees MH, et al., Nestin expression in pancreatic endocrine and exocrine cells of mice lacking glucagon signaling. Dev Dyn. 2007 Mar 15;236(4):1126-1133

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory