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Amy1
Gene Detail
Symbol

Name
ID
Member of
Amy1
amylase 1, salivary
MGI:88019
Amy cluster
Synonyms
Amy-1
Feature Type
protein coding gene
Genetic Map
Chromosome 3
49.35 cM
Detailed Genetic Map ± 1 cM


Mapping data(66)
Sequence Map
Chr3:113555710-113606699 bp, - strand
From VEGA annotation of GRCm38

  50990 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20179  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 2 cattle; 2 dog; 2 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: AMY2A
Gene Tree: Amy1

Human
homologs
AMY2A, amylase, alpha 2A (pancreatic)
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 279
neXtProt AC: NX_P04746

Human Synonyms: AMY2, PA

Human Chr (Location): 1p21; chr1:103617332-103625780 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(3) Transgenic(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Amy1 interacts with 76 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process carbohydrate catabolic process, carbohydrate metabolic process, ...
Component extracellular exosome, extracellular region, ...
Function alpha-amylase activity, amylase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (170)    Tissues (109)    Images (30)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 164
RT-PCR 6
cDNA source data(320)
Other mouse links: GEO   Expression Atlas
Molecular
reagents
All nucleic(331) Genomic(6) cDNA(320) Primer pair(3) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000022392 (Evidence)
Ensembl Gene Model ENSMUSG00000074264 (Evidence)
Entrez Gene 11722 (Evidence)
UniGene 439727
DFCI TC1572793
DoTS DT.111056656, DT.111056729, DT.111056757, DT.91443848, DT.94155725, DT.94166549, DT.97378097
EC 3.2.1.1
Consensus CDS Project CCDS17776.1
International Mouse Phenotyping Consortium Status Amy1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022392 VEGA Gene Model | MGI Sequence Detail 50990 C57BL/6J ±  kb
transcript OTTMUST00000053503 VEGA | MGI Sequence Detail 1985 Not Applicable 
polypeptide OTTMUSP00000025441 VEGA | MGI Sequence Detail 511 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(4) UniProt(4)
Polymorphisms
All PCR and RFLP(11) : PCR(2) RFLP(9) SNPs within 2kb(129 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006046 Alpha amylase
InterPro IPR006048 Alpha-amylase, C-terminal all beta
InterPro IPR013781 Glycoside hydrolase, catalytic domain
InterPro IPR015902 Glycoside hydrolase, family 13
InterPro IPR017853 Glycoside hydrolase, superfamily
InterPro IPR013780 Glycosyl hydrolase, family 13, all-beta
InterPro IPR006047 Glycosyl hydrolase, family 13, catalytic domain
InterPro IPR006589 Glycosyl hydrolase, family 13, subfamily, catalytic domain
Protein Ontology PR:000004569 alpha-amylase 1
References
(Earliest) J:12977 Sick K, et al., Genetics of amylase isozymes in the mouse. Hereditas. 1964;51:291-296
(Latest) J:219373 Islam MN, et al., Runx/Cbfb signaling regulates postnatal development of granular convoluted tubule in the mouse submandibular gland. Dev Dyn. 2015 Mar;244(3):488-96
All references(101)
Other
accession IDs
MGD-MRK-1313, MGD-MRK-1315

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory