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Amy1
Gene Detail
 Symbol
Name
ID
Member of
Amy1
amylase 1, salivary
MGI:88019
Amy cluster
Synonyms Amy-1
Feature Type protein coding gene
Genetic Map
Chromosome 3
49.35 cM
Detailed Genetic Map ± 1 cM


Mapping data(66)
Sequence Map
Chr3:113555710-113606699 bp, - strand
From VEGA annotation of GRCm38

  50990 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20179  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 2 cattle; 2 dog; 2 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Amy1

Human
homologs
Human Homolog AMY2A, amylase, alpha 2A (pancreatic)
NCBI Gene ID 279
neXtProt AC  NX_P04746
Human Synonyms  AMY2, AMY2B, PA
Human Chr (Location)  1p21; chr1:103617377-103625778 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Amy1 interacts with 76 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process carbohydrate catabolic process, carbohydrate metabolic process, ...
Component extracellular region, extracellular space, ...
Function alpha-amylase activity, amylase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (170)    Tissues (109)    Images (30)
Theiler Stages: 19, 21, 22, 23, 26, 28
Assay TypeResults
RNA in situ 164
RT-PCR 6
cDNA source data(320)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(331) Genomic(6) cDNA(320) Primer pair(3) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000022392 (Evidence)
Ensembl Gene ModelENSMUSG00000074264 (Evidence)
Entrez Gene11722 (Evidence)
UniGene439727
DFCITC1572793
DoTSDT.111056656, DT.111056729, DT.111056757, DT.91443848, DT.94155725, DT.94166549, DT.97378097
EC3.2.1.1
Consensus CDS ProjectCCDS17776.1
International Mouse Knockout Project StatusAmy1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022392 VEGA Gene Model | MGI Sequence Detail 50990 C57BL/6J ±  kb
transcript OTTMUST00000053503 VEGA | MGI Sequence Detail 1985 Not Applicable 
polypeptide OTTMUSP00000025441 VEGA | MGI Sequence Detail 511 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(4) UniProt(4)
Polymorphisms All PCR and RFLP(11) : PCR(2) RFLP(9) SNPs within 2kb(129 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006046 Alpha amylase
InterPro IPR006048 Alpha-amylase, C-terminal all beta
InterPro IPR013781 Glycoside hydrolase, catalytic domain
InterPro IPR015902 Glycoside hydrolase, family 13
InterPro IPR017853 Glycoside hydrolase, superfamily
InterPro IPR013780 Glycosyl hydrolase, family 13, all-beta
InterPro IPR006047 Glycosyl hydrolase, family 13, catalytic domain
InterPro IPR006589 Glycosyl hydrolase, family 13, subfamily, catalytic domain
Protein Ontology PR:000004569 alpha-amylase 1
References (Earliest) J:12977 Sick K, et al., Genetics of amylase isozymes in the mouse. Hereditas. 1964;51:291-296
(Latest) J:200656 Mead TJ, et al., A far-upstream (-70 kb) enhancer mediates Sox9 auto-regulation in somatic tissues during development and adult regeneration. Nucleic Acids Res. 2013 Apr;41(8):4459-69
All references(106)
Other
accession IDs
MGD-MRK-1313, MGD-MRK-1315

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory