Ampd1
Gene Detail

Symbol Name ID

Ampd1 adenosine monophosphate deaminase 1 MGI:88015

Synonyms

Ampd-1

Feature Type

protein coding gene

Genetic Map

Chromosome 3

45.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(9)

Sequence Map

Chr3:103074014-103099714 bp, + strand From VEGA annotation of GRCm38   25701 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Ampd1 ± 2 cM)

Protein SuperFamily: AMP deaminase
Gene Tree: Ampd1

Human ortholog

AMPD1 adenosine monophosphate deaminase 1 NCBI Gene ID 270
Human Synonyms: MAD, MADA
Human Chr1:115215719-115238239 bp, - strand Reference GRCh37.p2 Primary Assembly
Human Diseases Associated with Human AMPD1 (1)

Alleles and phenotypes

All alleles(27) : Targeted(1) Gene trapped(26)

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	IMP biosynthetic process, nucleotide metabolic process, ...
Component	cellular_component
Function	AMP deaminase activity, deaminase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (142)    Tissues (102)    Images (28)
Theiler Stages: 19, 21, 22, 23, 25, 28

Assay Type	Results
RNA in situ	134
RT-PCR	8

cDNA source data(14)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(18) cDNA(16) Primer pair(2)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000030299 (Evidence)
Ensembl Gene Model	ENSMUSG00000070385 (Evidence)
Entrez Gene	229665 (Evidence)
UniGene	331272
DFCI	TC1582766
DoTS	DT.40184118, DT.487835
NIA Mouse Gene Index	U227636
EC	3.5.4.6
Consensus CDS Project	CCDS38571.1
International Mouse Knockout Project Status	Ampd1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000030299	VEGA Gene Model | MGI Sequence Detail	25701	C57BL/6J
transcript	OTTMUST00000075010	VEGA | MGI Sequence Detail	2336	Not Applicable
polypeptide	OTTMUSP00000039252	VEGA | MGI Sequence Detail	745	Not Applicable

All sequences(33) RefSeq(2) UniProt(4)

Polymorphisms

RFLP(1) : SNPs(97 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR006650	Adenosine/AMP deaminase active site
InterPro	IPR001365	Adenosine/AMP deaminase domain
InterPro	IPR006329	AMP deaminase
Protein Ontology	PR:000004001	AMP deaminase 1

References

(Earliest) J:10446 Moseley WS, et al., Ampd-2 maps to distal mouse chromosome 3 in linkage with Ampd-1. Genomics. 1990 Mar;6(3):572-4
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(41)

Other accession IDs

MGD-MRK-1307, MGD-MRK-1309, MGI:2139757