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Ampd1
Gene Detail
Symbol

Name
ID
Ampd1
adenosine monophosphate deaminase 1
MGI:88015
Synonyms
Ampd-1
Feature Type
protein coding gene
Genetic Map
Chromosome 3
45.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(9)
Sequence Map
Chr3:103074014-103099714 bp, + strand
From VEGA annotation of GRCm38

  25701 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: AMP deaminase
Gene Tree: Ampd1

Human
homologs
Human Homolog AMPD1, adenosine monophosphate deaminase 1
NCBI Gene ID 270
neXtProt AC  NX_P23109
Human Synonyms  MAD, MADA, MMDD
Human Chr (Location)  1p13; chr1:114673098-114695618 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human AMPD1
Mutations,
alleles, and
phenotypes
All mutations/alleles(28) : Gene trapped(26) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process IMP salvage, nucleotide metabolic process, ...
Component cellular_component
Function AMP deaminase activity, deaminase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (142)    Tissues (103)    Images (28)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 134
RT-PCR 8
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(18) cDNA(16) Primer pair(2)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000030299 (Evidence)
Ensembl Gene ModelENSMUSG00000070385 (Evidence)
Entrez Gene229665 (Evidence)
UniGene331272
DFCITC1582766
DoTSDT.487835, DT.40184118
NIA Mouse Gene IndexU227636
EC3.5.4.6
Consensus CDS ProjectCCDS38571.1
International Mouse Knockout Project StatusAmpd1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030299 VEGA Gene Model | MGI Sequence Detail 25701 C57BL/6J ±  kb
transcript OTTMUST00000075010 VEGA | MGI Sequence Detail 2336 Not Applicable 
polypeptide OTTMUSP00000039252 VEGA | MGI Sequence Detail 745 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(6) UniProt(3)
Polymorphisms
RFLP(1) : SNPs within 2kb(122 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006650 Adenosine/AMP deaminase active site
InterPro IPR001365 Adenosine/AMP deaminase domain
InterPro IPR006329 AMP deaminase
Protein Ontology PR:000004001 AMP deaminase 1
References
(Earliest) J:10446 Moseley WS, et al., Ampd-2 maps to distal mouse chromosome 3 in linkage with Ampd-1. Genomics. 1990 Mar;6(3):572-4
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(43)
Other
accession IDs
MGD-MRK-1307, MGD-MRK-1309, MGI:2139757

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory