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Ak2
Gene Detail
 Symbol
Name
ID
Ak2
adenylate kinase 2
MGI:87978
Synonyms Ak-2, D4Ertd220e
Feature Type protein coding gene
Genetic Map
Chromosome 4
62.62 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr4:128991958-129011529 bp, + strand
From VEGA annotation of GRCm38

  19572 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1227  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: adenylate kinase
Gene Tree: Ak2

Human
homologs
Human Homolog AK2, adenylate kinase 2
NCBI Gene ID 204
neXtProt AC  NX_P54819
Human Synonyms  ADK2, AK 2
Human Chr (Location)  1p34; chr1:33007940-33036911 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human AK2
Alleles
and
phenotypes
All alleles(12) : Gene trapped(11) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process ADP biosynthetic process, AMP metabolic process, ...
Component cytosol, extracellular vesicular exosome, ...
Function adenylate kinase activity, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (245)    Tissues (155)    Images (41)
Theiler Stages: 22, 23, 28
Assay TypeResults
RNA in situ 199
RT-PCR 46
cDNA source data(238)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(242) cDNA(240) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000009623 (Evidence)
Ensembl Gene ModelENSMUSG00000028792 (Evidence)
Entrez Gene11637 (Evidence)
UniGene29460
DFCITC1572081, TC1584870
DoTSDT.101244545, DT.537175
NIA Mouse Gene IndexU004854
EC2.7.4.3
Consensus CDS ProjectCCDS18679.1, CCDS18680.1
International Mouse Knockout Project StatusAk2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009623 VEGA Gene Model | MGI Sequence Detail 19572 C57BL/6J ±  kb
transcript OTTMUST00000022144 VEGA | MGI Sequence Detail 986 Not Applicable 
polypeptide OTTMUSP00000010094 VEGA | MGI Sequence Detail 239 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(5) UniProt(2)
Polymorphisms SNPs within 2kb(327 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000850 Adenylate kinase
InterPro IPR007862 Adenylate kinase, active site lid domain
InterPro IPR006259 Adenylate kinase subfamily
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000003879 adenylate kinase 2, mitochondrial
References (Earliest) J:5872 Francke U, et al., Gene mapping in Mus musculus by interspecific cell hybridization: assignment of the genes for tripeptidase-1 to chromosome 10, dipeptidase-2 to chromosome 18, acid phosphatase-1 to chromosome 12, and adenylate kinase-1 to chromosome 2. Cytogenet Cell Genet. 1977;19(2-3):57-84
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(50)
Other
accession IDs
MGD-MRK-1241, MGD-MRK-1245, MGI:1098559

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory