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Ahcy
Gene Detail
 Symbol
Name
ID
Ahcy
S-adenosylhomocysteine hydrolase
MGI:87968
Synonyms CuBP, SAHH
Feature Type protein coding gene
Genetic Map
Chromosome 2
76.94 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr2:155059310-155074497 bp, - strand
From VEGA annotation of GRCm38

  15188 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:554  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: adenosylhomocysteine hydrolase, SAHH type
Gene Tree: Ahcy

Human
homologs
Human Homolog AHCY, adenosylhomocysteinase
NCBI Gene ID 191
neXtProt AC  NX_P23526
Human Synonyms  adoHcyase, SAHH
Human Chr (Location)  20q11.22; chr20:34280265-34311802 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human AHCY
Mutations,
alleles, and
phenotypes
All mutations/alleles(16) : Chemically and radiation induced(1) Gene trapped(12) Targeted(3)
Genomic Mutations involving Ahcy (1)
Incidental mutations (data from APF )
 
See the ax allele for a deletion that includes the Ahcy gene.
 
Interactions
Ahcy interacts with 149 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process chronic inflammatory response to antigenic stimulus, circadian sleep/wake cycle, ...
Component cytoplasm, cytosol, ...
Function adenosylhomocysteinase activity, adenyl nucleotide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (99)    Tissues (96)    Images (13)
Theiler Stages: 22, 23, 28
Assay TypeResults
RNA in situ 95
RT-PCR 4
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(16) Primer pair(1)
Microarray probesets(8)
Other database
links
VEGA Gene ModelOTTMUSG00000016006 (Evidence)
Ensembl Gene ModelENSMUSG00000027597 (Evidence)
Entrez Gene269378 (Evidence)
DFCITC1573178
DoTSDT.101267437, DT.101394055, DT.536995, DT.55195820
NIA Mouse Gene IndexU023529, U037082, U123670
Consensus CDS ProjectCCDS16942.1
International Mouse Knockout Project StatusAhcy
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016006 VEGA Gene Model | MGI Sequence Detail 15188 C57BL/6J ±  kb
transcript OTTMUST00000038111 VEGA | MGI Sequence Detail 2543 Not Applicable 
polypeptide OTTMUSP00000017088 VEGA | MGI Sequence Detail 432 Not Applicable 

For the selected sequences
All sequences(62) RefSeq(2)
Polymorphisms RFLP(2) : SNPs within 2kb(114 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000003854 adenosylhomocysteinase
References (Earliest) J:3225 Pilz A, et al., Mapping of the structural gene for S-adenosyl homocysteine hydrolase to mouse chromosome 2, and related sequences to chromosomes 8 and X. Mamm Genome. 1992;3(11):633-6
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(45)
Other
accession IDs
MGD-MRK-1202, MGI:2138395, MGI:2138825

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory