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Adss Gene Detail
Summary
  • Symbol
    Adss
  • Name
    adenylosuccinate synthetase, non muscle
  • Synonyms
    AS
  • Feature Type
    protein coding gene
  • IDs
    MGI:87948
    NCBI Gene: 11566
Location & Maps
more
  • Sequence Map
    Chr1:177762962-177796511 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      33550 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ADSS, adenylosuccinate synthase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ADSS, adenylosuccinate synthase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ADEH, ADSS 2
  • Links
    NCBI Gene ID: 159
    neXtProt AC: NX_P30520

  • Chr Location
    1q44; chr1:244408492-244452134 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    20
  • Chemically induced (other)
    2
  • Gene trapped
    12
  • Targeted
    6
  • Genomic Mutations
    2 involving Adss
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034836 VEGA Gene Model | MGI Sequence Detail 33550 C57BL/6J ±  kb
transcript OTTMUST00000088544 VEGA | MGI Sequence Detail 2771 Not Applicable  
polypeptide OTTMUSP00000048261 VEGA | MGI Sequence Detail 456 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    236 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000003795 adenylosuccinate synthetase isozyme 2
  • EC
  • InterPro Domains
    IPR033128 Adenylosuccinate synthase, active site
    IPR018220 Adenylosuccinate synthase, GTP-binding site
    IPR001114 Adenylosuccinate synthetase
    IPR027529 Adenylosuccinate synthetase isozyme 2, chordates
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
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  • All nucleic 145
    cDNA 145

    Microarray probesets 5
Other
Accession IDs
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MGD-MRK-1165, MGI:2138197
References
more
  • Summaries
    All 41
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 13
  • Earliest
    J:42300 Powell SM, et al., Cloning and characterization of the cDNA encoding human adenylosuccinate synthetase. FEBS Lett. 1992 May 25;303(1):4-10
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory