Plin2
Gene Detail

Symbol Name ID

Plin2 perilipin 2 MGI:87920

Synonyms

Adfp, adipophilin, ADPH, Adrp

Feature Type

protein coding gene

Genetic Map

Chromosome 4

40.69 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)

Sequence Map

Chr4:86648386-86670060 bp, - strand From VEGA annotation of GRCm38   21675 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Plin2 ± 2 cM)

Protein SuperFamily: lipid droplet-associated protein, perilipin type
Gene Tree: Plin2

Human ortholog

PLIN2 perilipin 2 NCBI Gene ID 123
Human Synonyms: ADFP, ADRP
Human Chr9:19115759-19127573 bp, - strand Reference GRCh37.p2 Primary Assembly

Alleles and phenotypes

All alleles(7) : Targeted(4) Gene trapped(3)
 

Male mice homozygous for one disruption in this gene are infertile while no comment is made regarding fertility for another such allele.

 

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	lipid storage, long-chain fatty acid transport
Component	cytoplasm, lipid particle, ...
Function	protein binding

External Resources: FuncBase

Expression

Literature Summary: (10 records)
Data Summary: Results (1)    Tissues (1)    Images (1)
Theiler Stages: 22

Assay Type	Results
RNA in situ	1

cDNA source data(368)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(380) Genomic(11) cDNA(368) Primer pair(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000007453 (Evidence)
Ensembl Gene Model	ENSMUSG00000028494 (Evidence)
Entrez Gene	11520 (Evidence)
UniGene	381
DFCI	TC1573348, TC1650896
DoTS	DT.101720511, DT.55104410, DT.97379230, DT.99867312
Consensus CDS Project	CCDS18308.1
International Mouse Knockout Project Status	Plin2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000007453	VEGA Gene Model | MGI Sequence Detail	21675	C57BL/6J
transcript	OTTMUST00000017238	VEGA | MGI Sequence Detail	1888	Not Applicable
polypeptide	OTTMUSP00000007962	VEGA | MGI Sequence Detail	425	Not Applicable

All sequences(71) RefSeq(2) UniProt(7)

Polymorphisms

All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs(75 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004279	Perilipin
Protein Ontology	PR:000003766	adipophilin

References

(Earliest) J:2265 Jiang HP, et al., Isolation and characterization of a full-length cDNA coding for an adipose differentiation-related protein. Proc Natl Acad Sci U S A. 1992 Sep 1;89(17):7856-60
(Latest) J:191941 Liu M, et al., Transient scrotal hyperthermia induces lipid droplet accumulation and reveals a different ADFP expression pattern between the testes and liver in mice. PLoS One. 2012;7(10):e45694
All references(67)

Other accession IDs

MGD-MRK-1110, MGD-MRK-1154, MGI:2140117