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Acy1 Gene Detail
Summary
  • Symbol
    Acy1
  • Name
    aminoacylase 1
  • Synonyms
    1110014J22Rik, Acy-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:87913
    NCBI Gene: 109652
  • Gene Overview
    MyGene.info: ACY1
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:106432981-106438236 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 57.49 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    136 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_87913
protein coding gene Chr9:106432981-106438319 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035229
protein coding gene Chr9:108241575-108246889 (-)
A/J MGP_AJ_G0035208
protein coding gene Chr9:104329722-104335037 (-)
AKR/J MGP_AKRJ_G0035140
protein coding gene Chr9:106928375-106933680 (-)
BALB/cJ MGP_BALBcJ_G0035202
protein coding gene Chr9:104014904-104020216 (-)
C3H/HeJ MGP_C3HHeJ_G0034912
protein coding gene Chr9:107339206-107345410 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035722
protein coding gene Chr9:111223240-111228578 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032620
protein coding gene Chr9:101819842-101825150 (-)
CAST/EiJ MGP_CASTEiJ_G0034223
protein coding gene Chr9:107244001-107249310 (-)
CBA/J MGP_CBAJ_G0034880
protein coding gene Chr9:115153696-115159034 (-)
DBA/2J MGP_DBA2J_G0035041
protein coding gene Chr9:103791694-103797011 (-)
FVB/NJ MGP_FVBNJ_G0034989
protein coding gene Chr9:102570763-102576073 (-)
LP/J MGP_LPJ_G0035117
protein coding gene Chr9:108461922-108467242 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035028
protein coding gene Chr9:116751832-116757147 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035743
protein coding gene Chr9:107176114-107181409 (-)
PWK/PhJ MGP_PWKPhJ_G0033930
protein coding gene Chr9:104088880-104094217 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033765
protein coding gene Chr9:107244156-107249452 (-)
WSB/EiJ MGP_WSBEiJ_G0034344
protein coding gene Chr9:107073823-107079118 (-)



Homology
more
  • Human Ortholog
    ACY1, aminoacylase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ACY1, aminoacylase 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ACY-1, ACY1D, HEL-S-5
  • Links
    NCBI Gene ID: 95
    neXtProt AC: NX_Q03154
    UniProt: Q03154

  • Chr Location
    3p21.2; chr3:51983284-51989202 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 109652 NCBI Gene Model | MGI Sequence Detail 5256 C57BL/6J ±  kb
transcript NM_025371 RefSeq | MGI Sequence Detail 1459 C57BL/6  
polypeptide Q99JW2 UniProt | EBI | MGI Sequence Detail 408 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 63
    Genomic 1
    cDNA 62

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-1099, MGD-MRK-1101, MGI:1913380
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:6118 Naylor SL, et al., Bioautographic visualization of aminoacylase-1: assignment of the structural gene ACY-1 to chromosome 3 in man. Somatic Cell Genet. 1979 Jan;5(1):11-21
  • Latest
    J:226616 Araujo DJ, et al., FoxP1 orchestration of ASD-relevant signaling pathways in the striatum. Genes Dev. 2015 Oct 15;29(20):2081-96

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory