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Acy1
Gene Detail
Symbol

Name
ID
Acy1
aminoacylase 1
MGI:87913
Synonyms
1110014J22Rik, Acy-1
Feature Type
protein coding gene
Genetic Map
Chromosome 9
57.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr9:106432981-106438319 bp, - strand
From VEGA annotation of GRCm38

  5339 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:110440  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: acyl-amino-acid amidohydrolase 1
Gene Tree: Acy1

Human
homologs
Human Homolog ACY1, aminoacylase 1
NCBI Gene ID 95
neXtProt AC  NX_Q03154
Human Synonyms  ACY-1, ACY1D, HEL-S-5
Human Chr (Location)  3p21.1; chr3:51983284-51989202 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human ACY1
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(5) Targeted(4)
Interactions
Acy1 interacts with 20 markers (Mir34a, Mir34b, Mir34c, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cellular amino acid metabolic process, metabolic process, ...
Component cytoplasm, extracellular vesicular exosome
Function aminoacylase activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(61)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(62) Genomic(1) cDNA(61)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000049425 (Evidence)
Ensembl Gene ModelENSMUSG00000023262 (Evidence)
Entrez Gene109652 (Evidence)
UniGene7165
DFCITC1579473
DoTSDT.532701, DT.94160172
NIA Mouse Gene IndexU031292
EC3.5.1.14
Consensus CDS ProjectCCDS23477.1
International Mouse Knockout Project StatusAcy1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049425 VEGA Gene Model | MGI Sequence Detail 5339 C57BL/6J ±  kb
transcript OTTMUST00000125998 VEGA | MGI Sequence Detail 1529 Not Applicable 
polypeptide OTTMUSP00000068185 VEGA | MGI Sequence Detail 408 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(4) UniProt(4)
Polymorphisms
SNPs within 2kb(154 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site
InterPro IPR010159 N-acyl-L-amino-acid amidohydrolase
InterPro IPR002933 Peptidase M20
InterPro IPR011650 Peptidase M20, dimerisation domain
Protein Ontology PR:000003703 aminoacylase-1
References
(Earliest) J:6118 Naylor SL, et al., Bioautographic visualization of aminoacylase-1: assignment of the structural gene ACY-1 to chromosome 3 in man. Somatic Cell Genet. 1979 Jan;5(1):11-21
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(41)
Other
accession IDs
MGD-MRK-1099, MGD-MRK-1101, MGI:1913380

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory