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Acy1 Gene Detail
Summary
  • Symbol
    Acy1
  • Name
    aminoacylase 1
  • Synonyms
    1110014J22Rik, Acy-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:87913
    NCBI Gene: 109652
  • Gene Overview
    MyGene.info: ACY1
Location & Maps
more
  • Sequence Map
    Chr9:106432981-106438319 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5339 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ACY1, aminoacylase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ACY1, aminoacylase 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ACY-1, ACY1D, HEL-S-5
  • Links
    NCBI Gene ID: 95
    neXtProt AC: NX_Q03154

  • Chr Location
    3p21.1; chr3:51983284-51989202 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human ACY1 associations

Human Disease Mouse Models
       Aminoacylase 1 Deficiency; ACY1D   OMIM: 609924
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    9
  • Gene trapped
    5
  • Targeted
    4
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049425 VEGA Gene Model | MGI Sequence Detail 5339 C57BL/6J ±  kb
transcript OTTMUST00000125998 VEGA | MGI Sequence Detail 1529 Not Applicable  
polypeptide OTTMUSP00000068185 VEGA | MGI Sequence Detail 408 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    141 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 62
    Genomic 1
    cDNA 61

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-1099, MGD-MRK-1101, MGI:1913380
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:6118 Naylor SL, et al., Bioautographic visualization of aminoacylase-1: assignment of the structural gene ACY-1 to chromosome 3 in man. Somatic Cell Genet. 1979 Jan;5(1):11-21
  • Latest
    J:226616 Araujo DJ, et al., FoxP1 orchestration of ASD-relevant signaling pathways in the striatum. Genes Dev. 2015 Oct 15;29(20):2081-96

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory