Acy1
Gene Detail

Symbol Name ID

Acy1 aminoacylase 1 MGI:87913

Synonyms

1110014J22Rik, Acy-1

Feature Type

protein coding gene

Genetic Map

Chromosome 9

57.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)

Sequence Map

Chr9:106432996-106438236 bp, - strand From NCBI annotation of GRCm38   5241 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; chimpanzee; dog, domestic; pig, domestic; rabbit, European    (Mammalian Orthology)
Comparative Map (Mouse/Human Acy1 ± 2 cM)

Protein SuperFamily: acyl-amino-acid amidohydrolase 1
Gene Tree: Acy1

Human ortholog

ACY1 aminoacylase 1 NCBI Gene ID 95
Human Synonyms: ACY-1, ACY1D
Human Chr3:52017563-52023218 bp, + strand Reference GRCh37.p2 Primary Assembly
Human Diseases Associated with Human ACY1 (1)

Alleles and phenotypes

All alleles(9) : Targeted(4) Gene trapped(5)

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	cellular amino acid metabolic process, metabolic process, ...
Component	cytoplasm
Function	aminoacylase activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22

Assay Type	Results
RNA in situ	94

cDNA source data(61)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(62) Genomic(1) cDNA(61)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000023262 (Evidence)
Entrez Gene	109652 (Evidence)
UniGene	7165
DFCI	TC1579473
DoTS	DT.532701, DT.94160172
NIA Mouse Gene Index	U031292
EC	3.5.1.14
Consensus CDS Project	CCDS23477.1
International Mouse Knockout Project Status	Acy1

Sequences

Length	Strain/Species
genomic	109652	NCBI Gene Model | MGI Sequence Detail	5241	C57BL/6J
transcript	NM_025371	RefSeq | MGI Sequence Detail	1459	C57BL/6
polypeptide	Q99JW2	UniProt | EBI | MGI Sequence Detail	408	Not Applicable

All sequences(19) RefSeq(4) UniProt(1)

Polymorphisms

SNPs(84 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001261	ArgE/DapE/ACY1/CPG2/YscS, conserved site
InterPro	IPR010159	N-acyl-L-amino-acid amidohydrolase
InterPro	IPR002933	Peptidase M20
InterPro	IPR011650	Peptidase M20, dimerisation
Protein Ontology	PR:000003703	aminoacylase-1

Graphical View of Protein Domain Structure

References

(Earliest) J:6118 Naylor SL, et al., Bioautographic visualization of aminoacylase-1: assignment of the structural gene ACY-1 to chromosome 3 in man. Somatic Cell Genet. 1979 Jan;5(1):11-21
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(39)

Other accession IDs

MGD-MRK-1099, MGD-MRK-1101, MGI:1913380