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Acat2
Gene Detail
 Symbol
Name
ID
Acat2
acetyl-Coenzyme A acetyltransferase 2
MGI:87871
Synonyms Tcp1-rs1, Tcp-1x
Feature Type protein coding gene
Genetic Map
Chromosome 17
8.73 cM, cytoband A2-A3
Detailed Genetic Map ± 1 cM


Mapping data(9)
Sequence Map
Chr17:12942890-12960747 bp, - strand
From VEGA annotation of GRCm38

  17858 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:130636  Vertebrate Homology Class
2 mouse; 1 rhesus macaque

Protein SuperFamily: acetyl-CoA acetyltransferase
Gene Tree: Acat2

Alleles
and
phenotypes
All alleles(4) : Targeted(3) Gene trapped(1)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process metabolic process
Component cytoplasm, mitochondrion
Function acetyl-CoA C-acetyltransferase activity, catalytic activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (327)    Tissues (131)    Images (66)
Theiler Stages: 22, 23, 26
Assay TypeResults
RNA in situ 327
cDNA source data(12)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(19) Genomic(5) cDNA(14)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000028085 (Evidence)
Ensembl Gene ModelENSMUSG00000023832 (Evidence)
Entrez Gene110460 (Evidence)
DoTSDT.536009, DT.101720591, DT.91482569
EC2.3.1.9
Consensus CDS ProjectCCDS37437.1
International Mouse Knockout Project StatusAcat2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028085 VEGA Gene Model | MGI Sequence Detail 17858 C57BL/6J ±  kb
transcript OTTMUST00000069567 VEGA | MGI Sequence Detail 2250 Not Applicable 
polypeptide OTTMUSP00000035353 VEGA | MGI Sequence Detail 397 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(2) UniProt(2)
Polymorphisms RFLP(2) : SNPs within 2kb(106 from dbSNP Build 137)    SNPs within 2kb including multiple locations(160)
Protein-related
information
ResourceIDDescription
InterPro IPR002155 Thiolase
InterPro IPR020610 Thiolase, active site
InterPro IPR020613 Thiolase, conserved site
InterPro IPR020617 Thiolase, C-terminal
InterPro IPR016039 Thiolase-like
InterPro IPR016038 Thiolase-like, subgroup
InterPro IPR020616 Thiolase, N-terminal
Protein Ontology PR:000003611 acetyl-CoA acetyltransferase, cytosolic
References (Earliest) J:8190 Willison KR, et al., Molecular cloning and sequence analysis of a haploid expressed gene encoding t complex polypeptide 1. Cell. 1986 Mar 14;44(5):727-38
(Latest) J:185622 Rogers MA, et al., Cellular pregnenolone esterification by acyl-CoA:cholesterol acyltransferase. J Biol Chem. 2012 May 18;287(21):17483-92
All references(46)
Other
accession IDs
MGD-MRK-1029, MGD-MRK-14817, MGD-MRK-14828, MGI:2147098, MGI:98537

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory