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ntl Gene Detail
Summary
  • Symbol
    ntl
  • Name
    new toothless
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:5702427
  • Alliance
Location & Maps
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  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 17, Syntenic
Human Diseases
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  • Diseases
    1 with ntl mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    14 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit failure of tooth eruption, osteopetrosis, enlarged liver, decreased body size and premature death unless fed a liquid diet.
References
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  • Summaries
    All 1
    Diseases 1
    Phenotypes 1
  • Earliest
    J:226596 Lu X, et al., A new osteopetrosis mutant mouse strain (ntl) with odontoma-like proliferations and lack of tooth roots. Eur J Oral Sci. 2009 Dec;117(6):625-35

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/17/2018
MGI 6.11
The Jackson Laboratory