Gm42674 Gene Detail

Summary

• Symbol
  Gm42674
• Name
  predicted gene 42674

• Feature Type
  protein coding gene
• IDs
  MGI:5662811
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr3:90509211-90513192 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 3, Syntenic

Strain
Comparison

• SNPs within 2kb
  57 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5662811	protein coding gene	Chr3:90509211-90513192 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0027474	protein coding gene	Chr3:90933418-90937385 (+)
A/J	MGP_AJ_G0027438	protein coding gene	Chr3:87898407-87902420 (+)
AKR/J	MGP_AKRJ_G0027403	protein coding gene	Chr3:90064562-90068533 (+)
BALB/cJ	MGP_BALBcJ_G0027447	protein coding gene	Chr3:87855142-87859563 (+)
C3H/HeJ	MGP_C3HHeJ_G0027189	protein coding gene	Chr3:90226298-90230269 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0027893	protein coding gene	Chr3:94338487-94342467 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025246	protein coding gene	Chr3:83400492-83404605 (+)
CAST/EiJ	MGP_CASTEiJ_G0026635	protein coding gene	Chr3:90623547-90627558 (+)
CBA/J	MGP_CBAJ_G0027164	protein coding gene	Chr3:97544813-97548793 (+)
DBA/2J	MGP_DBA2J_G0027301	protein coding gene	Chr3:87263830-87267853 (+)
FVB/NJ	MGP_FVBNJ_G0027269	protein coding gene	Chr3:85594277-85598255 (+)
LP/J	MGP_LPJ_G0027410	protein coding gene	Chr3:91990842-91994832 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027290	protein coding gene	Chr3:103787723-103791712 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0027952	protein coding gene	Chr3:89812062-89816084 (+)
PWK/PhJ	MGP_PWKPhJ_G0026369	protein coding gene	Chr3:87163287-87167331 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0026189	protein coding gene	Chr3:88992972-88996959 (+)
WSB/EiJ	MGP_WSBEiJ_G0026717	protein coding gene	Chr3:90217919-90221949 (+)

Homology

• Gene Tree
  Gm42674
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  4 phenotype references
  

• All Mutations and Alleles
  2
• Chemically induced (other)
  1
• Radiation induced
  1
• Genomic Mutations
  2 involving Gm42674
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  22
• UniProt
  1

• Ensembl
  ENSMUSG00000105518 (Evidence)

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000105518	Ensembl Gene Model | MGI Sequence Detail	3982	C57BL/6J
transcript	ENSMUST00000107330	Ensembl | MGI Sequence Detail	446	Not Applicable
polypeptide	ENSMUSP00000102953	Ensembl | MGI Sequence Detail	64	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR011992 EF-hand domain pair
  IPR001751 S100/Calcium binding protein 7/8-like, conserved site

References

• Summaries
  All 7

  Diseases 1

  Phenotypes 4
• Earliest
  J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
• Latest
  J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

TSS for Gm42674:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr30233	Chr3:90507510-90507526 (+)	-1,693 bp
Tssr30234	Chr3:90507544-90507554 (+)	-1,662 bp
Tssr30235	Chr3:90509080-90509116 (+)	-113 bp