Tmem265 Gene Detail

Summary

• Symbol
  Tmem265
• Name
  transmembrane protein 265

• Feature Type
  protein coding gene
• IDs
  MGI:5613213
  NCBI Gene: 105180375
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr7:127160395-127164443 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 7, Syntenic

Strain
Comparison

• SNPs within 2kb
  26 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5613213	protein coding gene	Chr7:127160395-127166112 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0033043	protein coding gene	Chr7:131921107-131926657 (+)
A/J	MGP_AJ_G0033026	protein coding gene	Chr7:128413437-128419015 (+)
AKR/J	MGP_AKRJ_G0032958	protein coding gene	Chr7:131718332-131723909 (+)
BALB/cJ	MGP_BALBcJ_G0033027	protein coding gene	Chr7:128059928-128065478 (+)
C3H/HeJ	MGP_C3HHeJ_G0032741	protein coding gene	Chr7:131620203-131625542 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0033536	protein coding gene	Chr7:137063133-137068639 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0030509	protein coding gene	Chr7:129601186-129606922 (+)
CAST/EiJ	MGP_CASTEiJ_G0032070	protein coding gene	Chr7:123416007-123421554 (+)
CBA/J	MGP_CBAJ_G0032714	protein coding gene	Chr7:141691424-141696986 (+)
DBA/2J	MGP_DBA2J_G0032866	protein coding gene	Chr7:126387217-126393048 (+)
FVB/NJ	MGP_FVBNJ_G0032819	protein coding gene	Chr7:126232875-126238416 (+)
LP/J	MGP_LPJ_G0032960	protein coding gene	Chr7:133398826-133404951 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0032851	protein coding gene	Chr7:142809450-142814986 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0033556	protein coding gene	Chr7:130713769-130719320 (+)
PWK/PhJ	MGP_PWKPhJ_G0031777	protein coding gene	Chr7:119396422-119402032 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0031623	protein coding gene	Chr7:117522089-117527673 (+)
WSB/EiJ	MGP_WSBEiJ_G0032182	protein coding gene	Chr7:131680638-131686179 (+)

Homology

• Human Ortholog
  TMEM265, transmembrane protein 265

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  TMEM265, transmembrane protein 265
  
• Synonyms
  IFITMD8
• Links
  HGNC:51241

  NCBI Gene ID: 100862671

  neXtProt AC: NX_A0A087WTH1

  UniProt: A0A087WTH1

  
  
• Chr Location
  16p11.2; chr16:30740642-30745196 (+)  GRCh38

---

• MGI Vertebrate Homology
  Tmem265 stringent orthology
  1 human;1 mouse;1 zebrafish
  
• HCOP
  vertebrate homology predictions: TMEM265
• Gene Tree
  Tmem265
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  3 strains or lines available

Expression

• Assay Results
  706
• cDNA Data
  5

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  33
• RefSeq
  2
• UniProt
  2
• CCDS
  CCDS80807.1

• Ensembl
  ENSMUSG00000106715 (Evidence)
• NCBI Gene
  105180375

Representative Sequences			Length	Strain/Species
genomic	105180375	NCBI Gene Model | MGI Sequence Detail	4049	C57BL/6J
transcript	NM_001304267	RefSeq | MGI Sequence Detail	1251	ZRU/MplStud
polypeptide	NP_001291196	RefSeq | MGI Sequence Detail	109	ZRU/MplStud

Protein
Information

• UniProt
  2 Sequences
• InterPro Domains
  IPR007593 CD225/Dispanin family

Molecular
Reagents

• All nucleic 5

  cDNA 5

References

• Summaries
  All 9

  Phenotypes 1
• Earliest
  J:23000 MGD Nomenclature Committee, Nomenclature Committee Use. 1995-02-14;
• Latest
  J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8;

TSS for Tmem265:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr69253	Chr7:127160902-127160914 (+)	513 bp
Tssr2407	Chr7:127160923-127160936 (+)	535 bp