Armc4
Gene Detail

Symbol Name ID

Armc4 armadillo repeat containing 4 MGI:1922184

Synonyms

4930463I21Rik, b2b227.1Clo, b2b643Clo

Feature Type

protein coding gene

Genetic Map

Chromosome 18

4.53 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr18:7088233-7297901 bp, - strand From NCBI annotation of GRCm38   209669 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:9992  Vertebrate Homology Class
1 human; 1 mouse; 1 rhesus macaque; 1 cattle; 2 dog; 1 chicken

Gene Tree: Armc4

Human homologs

Human Homolog		ARMC4, armadillo repeat containing 4
NCBI Gene ID		55130
neXtProt AC		NX_Q5T2S8
Human Chr (Location)		10p12.1-p11.23; chr10:28101097-28287977 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(6) : Targeted(2) Gene trapped(2) Chemically induced(2)
 

Mice homozygous for ENU-induced mutations exhibit situs inversus totalis, or heterotaxy with congenital heart disease, including double outlet right ventricle (DORV) and perimembranous ventricular septal defects (VSD). Dyskinetic, slow, or immotile airway cilia are also seen.

 
Human Diseases Modeled Using Mouse Armc4 (1)    Alleles Annotated to Human Diseases(1)    Phenotype Images(24)

Gene Ontology (GO) classifications

All GO classifications: (3 annotations)

Process	biological_process
Component	cellular_component
Function	molecular_function

External Resources: FuncBase

Expression

cDNA source data(2)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(2) cDNA(2)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000061802 (Evidence)
Entrez Gene	74934 (Evidence)
DFCI	TC1602316, TC1675043
DoTS	DT.60108267, DT.87041734
NIA Mouse Gene Index	U079256
Consensus CDS Project	CCDS37729.1
International Mouse Knockout Project Status	Armc4

Sequences

Length	Strain/Species
genomic	74934	NCBI Gene Model | MGI Sequence Detail	209669	C57BL/6J
transcript	NM_001081393	RefSeq | MGI Sequence Detail	3477	Not Specified
polypeptide	NP_001074862	RefSeq | MGI Sequence Detail	1037	Not Specified

All sequences(16) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(650 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000225	Armadillo
InterPro	IPR011989	Armadillo-like helical
InterPro	IPR026959	Armadillo repeat-containing protein 4
InterPro	IPR016024	Armadillo-type fold
Protein Ontology	PR:000030558	armadillo repeat-containing protein 4

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
All references(23)

Other accession IDs

MGI:5311339, MGI:5437094