Entpd4b Gene Detail

Summary

• Symbol
  Entpd4b
• Name
  ectonucleoside triphosphate diphosphohydrolase 4B
• Synonyms
  Gm21685

• Feature Type
  protein coding gene
• IDs
  MGI:5435040
  NCBI Gene: 100862375
• Alliance
  genome feature page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr14:69792850-69822389 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 14, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• Strain Annotations
  9

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5435040	protein coding gene	Chr14:69792850-69822969 (+)
129S1/SvImJ	no annotation
A/J	ENSMUSG00195013391	protein coding gene	Chr14:58365714-58395810 (+)
AKR/J	ENSMUSG00220029498	protein coding gene	Chr14:57701476-57731575 (+)
BALB/cJ	no annotation
C3H/HeJ	ENSMUSG00175032002	protein coding gene	Chr14:59734889-59764985 (+)
C57BL/6NJ	no annotation
CAROLI/EiJ	MGP_CAROLIEiJ_G0019464	protein coding gene	Chr14:60434374-60683991 (+)
CAST/EiJ	no annotation
CBA/J	ENSMUSG00210039098	protein coding gene	Chr14:58350733-58380830 (+)
DBA/2J	no annotation
FVB/NJ	ENSMUSG00205032149	protein coding gene	Chr14:57860189-57890286 (+)
JF1/MsJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	ENSMUSG00190030437	protein coding gene	Chr14:58145529-58175626 (+)
NZO/HlLtJ	ENSMUSG00225039747	protein coding gene	Chr14:65872799-65902895 (+)
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Human Ortholog
  ENTPD4, ectonucleoside triphosphate diphosphohydrolase 4

• Vertebrate Orthologs
  1

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  ENTPD4, ectonucleoside triphosphate diphosphohydrolase 4
  
• Synonyms
  LALP70, LAP70, LYSAL1, NTPDase-4, UDPase
• Links
  HGNC:14573

  NCBI Gene ID: 9583

  UniProt: Q9Y227

  
  
• Chr Location
  8p21.3; chr8:23385783-23457716 (-)  GRCh38

---

• MGI Vertebrate Homology
  Entpd4b stringent orthology
  1 human;1 mouse
  
• HCOP
  vertebrate homology predictions: ENTPD4
• Gene Tree
  Entpd4b
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotype references
  

• All Mutations and Alleles
  5
• Chemically induced (other)
  1
• Targeted
  4
• Genomic Mutations
  1 involving Entpd4b
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  24
• RefSeq
  4
• CCDS
  CCDS88700.1

• Ensembl
  ENSMUSG00000022066 (Evidence)
• NCBI Gene
  100862375

Representative Sequences			Length	Strain/Species
genomic	100862375	NCBI Gene Model | MGI Sequence Detail	29540	C57BL/6J
transcript	NM_001359159	RefSeq | MGI Sequence Detail	3032	ZRU/MplStud
polypeptide	NP_001346088	RefSeq | MGI Sequence Detail	613	ZRU/MplStud

Other
Accession IDs

MGI:5883591

References

• Summaries
  All 9

  Phenotypes 3
• Earliest
  J:23389 Roderick TH, Using inversions to detect and study recessive lethals and detrimentals in mice, in Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk. 1983:135-67.
• Latest
  J:389486 Mouse Genome Informatics and Ensembl Genome Database Project, MGI Strain Genome Feature and Gene Model Load from Ensembl. Database Release. 2026;

TSS for Entpd4b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr126373	Chr14:69792826-69792930 (+)	28 bp
Tssr164713	Chr14:69794259-69794270 (+)	1,415 bp