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Gm572 Gene Detail
Summary
  • Symbol
    Gm572
  • Name
    predicted gene 572
  • Synonyms
    b2b1167Clo, LOC230909
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685418
    NCBI Gene: 230909
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr4:148643317-148671572 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      28256 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 78.82 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    C1orf127, chromosome 1 open reading frame 127
  • Vertebrate Orthologs
    6
  • Human Ortholog
    C1orf127, chromosome 1 open reading frame 127
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 148345
    neXtProt AC: NX_Q8N9H9
    UniProt: Q8N9H9

  • Chr Location
    1p36.22; chr1:10946473-10982037 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    3 with Gm572 mouse models

Human Disease Mouse Models
      
IDs
View 1 model
IDs
View 1 model
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    22 images
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for an ENU-induced allele show cardiovascular defects including double outlet right ventricle, dextrocardia and atrioventricular septal defects, heterotaxia with situs inversus totalis and right pulmonary isomerism, spleen hypoplasia, mid-line liver, and immotile respiratory cilia.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010944 VEGA Gene Model | MGI Sequence Detail 28256 C57BL/6J ±  kb
transcript OTTMUST00000025665 VEGA | MGI Sequence Detail 1385 Not Applicable  
polypeptide OTTMUSP00000011763 VEGA | MGI Sequence Detail 399 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    363 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR027956 Protein of unknown function DUF4556
Molecular
Reagents
less

  • Microarray probesets 1
Other
Accession IDs
less
MGI:5431486
References
more
  • Summaries
    All 17
    Diseases 1
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:222159 Li Y, et al., Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Nature. 2015 May 28;521(7553):520-4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory