Tmppe Gene Detail

Summary

• Symbol
  Tmppe
• Name
  transmembrane protein with metallophosphoesterase domain

• Feature Type
  protein coding gene
• IDs
  MGI:5317335
  NCBI Gene: 100504715
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr9:114401105-114407276 bp, + strand
• From Ensembl annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 9, 64.40 cM

Strain
Comparison

• SNPs within 2kb
  37 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5317335	protein coding gene	Chr9:114401095-114411201 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0035387	protein coding gene	Chr9:116816422-116830659 (+)
A/J	MGP_AJ_G0035367	protein coding gene	Chr9:112557946-112568044 (+)
AKR/J	MGP_AKRJ_G0035300	protein coding gene	Chr9:115413307-115423305 (+)
BALB/cJ	MGP_BALBcJ_G0035363	protein coding gene	Chr9:112354990-112365004 (+)
C3H/HeJ	MGP_C3HHeJ_G0035071	protein coding gene	Chr9:115925816-115937149 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0035886	protein coding gene	Chr9:120020129-120030152 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0032769	protein coding gene	Chr9:109861944-109871308 (+)
CAST/EiJ	MGP_CASTEiJ_G0034376	protein coding gene	Chr9:115763971-115775589 (+)
CBA/J	MGP_CBAJ_G0035038	protein coding gene	Chr9:124508669-124518684 (+)
DBA/2J	MGP_DBA2J_G0035197	protein coding gene	Chr9:112033588-112043634 (+)
FVB/NJ	MGP_FVBNJ_G0035144	protein coding gene	Chr9:110847029-110857821 (+)
LP/J	MGP_LPJ_G0035276	protein coding gene	Chr9:117174863-117184849 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0035185	protein coding gene	Chr9:125754506-125764583 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0035905	protein coding gene	Chr9:115779348-115790309 (+)
PWK/PhJ	MGP_PWKPhJ_G0034082	protein coding gene	Chr9:112332409-112342437 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0033916	protein coding gene	Chr9:115828196-115840020 (+)
WSB/EiJ	MGP_WSBEiJ_G0034496	protein coding gene	Chr9:115664575-115677256 (+)

Homology

• Human Ortholog
  TMPPE, transmembrane protein with metallophosphoesterase domain

• Vertebrate Orthologs
  8

• Human Ortholog
  TMPPE, transmembrane protein with metallophosphoesterase domain
  Orthology source: HomoloGene, HGNC
• Links
  HGNC:33865

  NCBI Gene ID: 643853

  neXtProt AC: NX_Q6ZT21

  UniProt: Q6ZT21

  
  
• Chr Location
  3p22.3; chr3:33090416-33096801 (-)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 62675
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 chicken;1 zebrafish;1 macaque, rhesus
  
• HCOP
  human homology predictions: TMPPE
• Gene Tree
  Tmppe
  

Mutations,
Alleles, and
Phenotypes

• Incidental Mutations
  APF
• Find Mice (IMSR)
  5 strains or lines available

Expression

• Assay Results
  631
• cDNA Data
  3

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Interactions

• Tmppe interacts with 368 markers (Mir1b, Mir7-1, Mir7-2, ...) View All

Sequences &
Gene Models

• All Sequences
  29
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS52951.1

• Ensembl
  ENSMUSG00000079260 (Evidence)
• NCBI Gene
  100504715

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000079260	Ensembl Gene Model | MGI Sequence Detail	6172	C57BL/6J
transcript	ENSMUST00000111820	Ensembl | MGI Sequence Detail	2921	Not Applicable
polypeptide	ENSMUSP00000107451	Ensembl | MGI Sequence Detail	447	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR004843 Calcineurin-like phosphoesterase domain, ApaH type
  IPR029052 Metallo-dependent phosphatase-like

Molecular
Reagents

• All nucleic 3

  cDNA 3

References

• Summaries
  All 9
• Earliest
  J:23000 MGD Nomenclature Committee, 2/14/1995;
• Latest
  J:155721 Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI), Consensus CDS project. Database Download. 2010;