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Tmppe Gene Detail
Summary
  • Symbol
    Tmppe
  • Name
    transmembrane protein with metallophosphoesterase domain
  • Feature Type
    protein coding gene
  • IDs
    MGI:5317335
    NCBI Gene: 100504715
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:114230173-114236344 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 64.40 cM
Strain
Comparison
more
  • SNPs within 2kb
    290 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_5317335
 protein coding gene Chr9:114230163-114240269 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035387
 protein coding gene Chr9:116816422-116830659 (+)
A/J MGP_AJ_G0035367
 protein coding gene Chr9:112557946-112568044 (+)
AKR/J MGP_AKRJ_G0035300
 protein coding gene Chr9:115413307-115423305 (+)
BALB/cJ MGP_BALBcJ_G0035363
 protein coding gene Chr9:112354990-112365004 (+)
C3H/HeJ MGP_C3HHeJ_G0035071
 protein coding gene Chr9:115925816-115937149 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035886
 protein coding gene Chr9:120020129-120030152 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032769
 protein coding gene Chr9:109861944-109871308 (+)
CAST/EiJ MGP_CASTEiJ_G0034376
 protein coding gene Chr9:115763971-115775589 (+)
CBA/J MGP_CBAJ_G0035038
 protein coding gene Chr9:124508669-124518684 (+)
DBA/2J MGP_DBA2J_G0035197
 protein coding gene Chr9:112033588-112043634 (+)
FVB/NJ MGP_FVBNJ_G0035144
 protein coding gene Chr9:110847029-110857821 (+)
LP/J MGP_LPJ_G0035276
 protein coding gene Chr9:117174863-117184849 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035185
 protein coding gene Chr9:125754506-125764583 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035905
 protein coding gene Chr9:115779348-115790309 (+)
PWK/PhJ MGP_PWKPhJ_G0034082
 protein coding gene Chr9:112332409-112342437 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033916
 protein coding gene Chr9:115828196-115840020 (+)
WSB/EiJ MGP_WSBEiJ_G0034496
 protein coding gene Chr9:115664575-115677256 (+)



Homology
more
  • Human Ortholog
    TMPPE, transmembrane protein with metallophosphoesterase domain
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMPPE, transmembrane protein with metallophosphoesterase domain
  • Links
    NCBI Gene ID: 643853
    UniProt: Q6ZT21

  • Chr Location
    3p22.3; chr3:33090421-33097146 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000079260 Ensembl Gene Model | MGI Sequence Detail 6172 C57BL/6J ±  kb
transcript ENSMUST00000111820 Ensembl | MGI Sequence Detail 2921 Not Applicable  
polypeptide ENSMUSP00000107451 Ensembl | MGI Sequence Detail 447 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR004843 Calcineurin-like phosphoesterase domain, ApaH type
    IPR029052 Metallo-dependent phosphatase-like
    IPR051158 Metallophosphoesterase superfamily
  • GlyGen
    D3Z286 1 site
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3
References
more
  • Summaries
    All 10
    Phenotypes 1
  • Earliest
    J:23000 MGD Nomenclature Committee, Nomenclature Committee Use. 1995-02-14;
  • Latest
    J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory