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Daw1
Gene Detail
Symbol

Name
ID
Daw1
dynein assembly factor with WDR repeat domains 1
MGI:1923089
Synonyms
4930563E19Rik, 4933429D11Rik, b2b1116Clo, Wdr69
Feature Type
protein coding gene
Genetic Map
Chromosome 1
42.70 cM, cytoband C5
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:83159752-83210574 bp, + strand
From VEGA annotation of GRCm38

  50823 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HCOP human homology predictions: DAW1
Gene Tree: Daw1
Human
homologs
DAW1, dynein assembly factor with WDR repeat domains 1
Orthology source: HGNC

IDs:
NCBI Gene ID: 164781
neXtProt AC: NX_Q8N136

Human Synonyms: ODA16, WDR69

Human Chr (Location): 2q36.3; chr2:227871054-227924347 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Chemically induced (ENU)(1)
Incidental mutations (data from APF , CvDC )
 
Mice homozygous for an induced mutation exhibit dextrocardia associated with situs inversus totalis, overriding aorta, ventricular septal defects, and dual inferior vena cava as well as dextrogastria, hypoplastic spleen, inverted liver, lung lobation/isomerism and dyskinetic/immotile airway cilia
 
Phenotype Images(21)
Interactions
Daw1 interacts with 215 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process biological_process
Component cellular_component
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(7)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase daw1 ; ZFIN daw1    NEW 
Molecular
reagents
All nucleic(7) cDNA(7)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000022978 (Evidence)
Ensembl Gene Model ENSMUSG00000053161 (Evidence)
Entrez Gene 71227 (Evidence)
UniGene 256482
DFCI TC1591857, TC1588046
DoTS DT.101189056, DT.101362086, DT.55180340
NIA Mouse Gene Index U000513
Consensus CDS Project CCDS15103.1
International Mouse Phenotyping Consortium Status Daw1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022978 VEGA Gene Model | MGI Sequence Detail 50823 C57BL/6J ±  kb
transcript OTTMUST00000064965 VEGA | MGI Sequence Detail 1651 Not Applicable 
polypeptide OTTMUSP00000032315 VEGA | MGI Sequence Detail 415 Not Applicable 

For the selected sequences
All sequences(55) RefSeq(16) UniProt(6)
Polymorphisms
SNPs within 2kb(288 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020472 G-protein beta WD-40 repeat
InterPro IPR001680 WD40 repeat
InterPro IPR019775 WD40 repeat, conserved site
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000031393 dynein assembly factor with WDR repeat domains 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
All references(21)
Other
accession IDs
MGI:1918477, MGI:5311348

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory