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Pakap Gene Detail
Summary
  • Symbol
    Pakap
  • Name
    paralemmin A kinase anchor protein
  • Synonyms
    53-H12, AF064781, Akap2, AKAP-KL, B230340M18Rik, Gm20459, Palm2, Palm2Akap2, Palm2-Akap2, pEN70
  • Feature Type
    protein coding gene
  • IDs
    MGI:5141924
    NCBI Gene: 677884
  • Alliance
  • Transcription Start Sites
    19 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:57568248-57896984 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 31.66 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2480 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_5141924
protein coding gene Chr4:57434247-57896984 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028318
protein coding gene Chr4:56377204-56708277 (+)
A/J MGP_AJ_G0028279
protein coding gene Chr4:54221311-54554981 (+)
AKR/J MGP_AKRJ_G0028228
protein coding gene Chr4:55720929-56060396 (+)
BALB/cJ MGP_BALBcJ_G0028298
protein coding gene Chr4:54385554-54716958 (+)
C3H/HeJ MGP_C3HHeJ_G0028019
protein coding gene Chr4:56232612-56569843 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028739
protein coding gene Chr4:58375333-58739112 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026045
protein coding gene Chr4:51010248-51332233 (+)
CAST/EiJ MGP_CASTEiJ_G0027457
protein coding gene Chr4:55953075-56300926 (+)
CBA/J MGP_CBAJ_G0027984
protein coding gene Chr4:60395680-60729783 (+)
DBA/2J MGP_DBA2J_G0028134
protein coding gene Chr4:54122845-54453048 (+)
FVB/NJ MGP_FVBNJ_G0028101
protein coding gene Chr4:53351481-53679573 (+)
LP/J MGP_LPJ_G0028233
protein coding gene Chr4:56476834-56822514 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028125
protein coding gene Chr4:63519436-63865087 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028775
protein coding gene Chr4:55917842-56265863 (+)
PWK/PhJ MGP_PWKPhJ_G0027182
protein coding gene Chr4:54130572-54455786 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027010
protein coding gene Chr4:55189601-55535837 (+)
WSB/EiJ MGP_WSBEiJ_G0027535
protein coding gene Chr4:55858179-56215098 (+)



Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 677884 NCBI Gene Model | MGI Sequence Detail 328737 C57BL/6J ±  kb
transcript NM_172868 RefSeq | MGI Sequence Detail 8213 C57BL/6  
polypeptide O54931 UniProt | EBI | MGI Sequence Detail 893 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    12 Sequences
  • InterPro Domains
    IPR029304 A-kinase anchor protein 2, C-terminal domain
    IPR004965 Paralemmin
Molecular
Reagents
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  • All nucleic 30
    cDNA 29
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
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MGI:1306795, MGI:1934601, MGI:2140178, MGI:2140348, MGI:2140719, MGI:2443506, MGI:3845895
References
more
  • Summaries
    All 37
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:46555 Dong F, et al., Molecular characterization of a cDNA that encodes six isoforms of a novel murine A kinase anchor protein. J Biol Chem. 1998 Mar 13;273(11):6533-41
  • Latest
    J:231595 Gurdziel K, et al., Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun. Dev Dyn. 2016 May;245(5):614-26

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory