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Heatr4 Gene Detail
Summary
  • Symbol
    Heatr4
  • Name
    HEAT repeat containing 4
  • Synonyms
    Gm17673
  • Feature Type
    protein coding gene
  • IDs
    MGI:4937307
    NCBI Gene: 101055670
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:84001273-84031626 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 38.98 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    867 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4937307
 protein coding gene Chr12:83991987-84031643 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019921
 protein coding gene Chr12:84621069-84653023 (-)
A/J MGP_AJ_G0019878
 protein coding gene Chr12:81414956-81442860 (-)
AKR/J MGP_AKRJ_G0019854
 protein coding gene Chr12:83621537-83652585 (-)
BALB/cJ MGP_BALBcJ_G0019858
 protein coding gene Chr12:81758942-81786023 (-)
C3H/HeJ MGP_C3HHeJ_G0019664
 protein coding gene Chr12:84081040-84112195 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020310
 protein coding gene Chr12:87039916-87071370 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017927
 protein coding gene Chr12:78338436-78366803 (-)
CAST/EiJ MGP_CASTEiJ_G0019213
 protein coding gene Chr12:79022335-79055247 (-)
CBA/J MGP_CBAJ_G0019635
 protein coding gene Chr12:90376332-90410139 (-)
DBA/2J MGP_DBA2J_G0019750
 protein coding gene Chr12:80957923-80987763 (-)
FVB/NJ MGP_FVBNJ_G0019736
 protein coding gene Chr12:79905028-79934119 (-)
LP/J MGP_LPJ_G0019822
 protein coding gene Chr12:84495037-84525807 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019775
 protein coding gene Chr12:93356275-93387326 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020344
 protein coding gene Chr12:83209870-83240694 (-)
PWK/PhJ MGP_PWKPhJ_G0018977
 protein coding gene Chr12:75439227-75467974 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018772
 protein coding gene Chr12:77697355-77724318 (-)
WSB/EiJ MGP_WSBEiJ_G0019265
 protein coding gene Chr12:83894884-83924633 (-)



Homology
more
  • Human Ortholog
    HEATR4, HEAT repeat containing 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HEATR4, HEAT repeat containing 4
  • Links
    NCBI Gene ID: 399671
    UniProt: Q86WZ0

  • Chr Location
    chr14:73478484-73633814 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      27
    • RefSeq
      4
    • UniProt
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000090843 Ensembl Gene Model | MGI Sequence Detail 30354 C57BL/6J ±  kb
    transcript ENSMUST00000164935 Ensembl | MGI Sequence Detail 3038 Not Applicable  
    polypeptide ENSMUSP00000129832 Ensembl | MGI Sequence Detail 955 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR011989 Armadillo-like helical
      IPR016024 Armadillo-type fold
    References
    more
    • Summaries
      All 11
      Gene Ontology 1
      Phenotypes 4
    • Earliest
      J:23389 Roderick TH, Using inversions to detect and study recessive lethals and detrimentals in mice, in Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk. 1983:135-67.
    • Latest
      J:211773 Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC), Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database. Database Release. 2014-2024;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory