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Dthd1 Gene Detail
Summary
  • Symbol
    Dthd1
  • Name
    death domain containing 1
  • Synonyms
    Gm17384
  • Feature Type
    protein coding gene
  • IDs
    MGI:4937018
    NCBI Gene: 100322896
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr5:62811674-62888308 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 32.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    573 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4937018
protein coding gene Chr5:62811656-62888318 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029561
protein coding gene Chr5:62354011-62434652 (+)
A/J MGP_AJ_G0029529
protein coding gene Chr5:59986422-60058726 (+)
AKR/J MGP_AKRJ_G0029477
protein coding gene Chr5:61875244-61952212 (+)
BALB/cJ MGP_BALBcJ_G0029538
protein coding gene Chr5:60675963-60748207 (+)
C3H/HeJ MGP_C3HHeJ_G0029261
protein coding gene Chr5:62211303-62286539 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029992
protein coding gene Chr5:64940349-65019694 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027232
protein coding gene Chr5:56201628-56270871 (+)
CAST/EiJ MGP_CASTEiJ_G0028669
protein coding gene Chr5:61301692-61379702 (+)
CBA/J MGP_CBAJ_G0029230
protein coding gene Chr5:67004224-67090909 (+)
DBA/2J MGP_DBA2J_G0029376
protein coding gene Chr5:60048156-60123472 (+)
FVB/NJ MGP_FVBNJ_G0029336
protein coding gene Chr5:59247998-59323250 (+)
LP/J MGP_LPJ_G0029461
protein coding gene Chr5:62807848-62882370 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029364
protein coding gene Chr5:69836897-69927068 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030025
protein coding gene Chr5:61608749-61694800 (+)
PWK/PhJ MGP_PWKPhJ_G0028393
protein coding gene Chr5:59068270-59138866 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028227
protein coding gene Chr5:60952374-61027520 (+)
WSB/EiJ MGP_WSBEiJ_G0028750
protein coding gene Chr5:61777118-61863501 (+)



Homology
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  • Human Ortholog
    DTHD1, death domain containing 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DTHD1, death domain containing 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 401124
    neXtProt AC: NX_Q6ZMT9
    UniProt: Q6ZMT9

  • Chr Location
    4p14; chr4:36281593-36347511 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    19 phenotype references
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000090326 Ensembl Gene Model | MGI Sequence Detail 76635 C57BL/6J ±  kb
transcript ENSMUST00000238474 Ensembl | MGI Sequence Detail 2877 Not Applicable  
polypeptide ENSMUSP00000158635 Ensembl | MGI Sequence Detail 905 Not Applicable  
For the selected sequence
Protein
Information
less
References
more
  • Summaries
    All 26
    Phenotypes 19
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:125425 Howell GR, et al., Mutation of a ubiquitously expressed mouse transmembrane protein (Tapt1) causes specific skeletal homeotic transformations. Genetics. 2007 Feb;175(2):699-707

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory