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Trim12c Gene Detail
Summary
  • Symbol
    Trim12c
  • Name
    tripartite motif-containing 12C
  • Synonyms
    9230105E10Rik, Trim12-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:4821183
    NCBI Gene: 319236
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:103987961-104002569 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 55.69 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    178 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4821183
 protein coding gene Chr7:103987961-104002649 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032712
 protein coding gene Chr7:107487990-107504620 (-)
A/J MGP_AJ_G0032687
 protein coding gene Chr7:104673998-104689788 (-)
AKR/J MGP_AKRJ_G0032620
 protein coding gene Chr7:107299130-107313285 (-)
BALB/cJ MGP_BALBcJ_G0032697
 protein coding gene Chr7:104405926-104422346 (-)
C3H/HeJ MGP_C3HHeJ_G0032408
 protein coding gene Chr7:107553360-107569699 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033191
 protein coding gene Chr7:111546095-111623885 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030187
 protein coding gene Chr7:106765939-106780265 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0032376
 protein coding gene Chr7:115465613-115480018 (-)
DBA/2J MGP_DBA2J_G0032530
 protein coding gene Chr7:103009098-103023960 (-)
FVB/NJ MGP_FVBNJ_G0032483
 protein coding gene Chr7:102718373-102734009 (-)
LP/J MGP_LPJ_G0032623
 protein coding gene Chr7:108816383-108833425 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032515
 protein coding gene Chr7:116853711-116960149 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033220
 protein coding gene Chr7:106482851-106501434 (-)
PWK/PhJ MGP_PWKPhJ_G0031451
 protein coding gene Chr7:96006091-96025569 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031297
 protein coding gene Chr7:93626329-93644803 (-)
WSB/EiJ MGP_WSBEiJ_G0031852
 protein coding gene Chr7:107144827-107163615 (-)



Homology
more
  • Human Ortholog
    TRIM5, tripartite motif containing 5
  • Vertebrate Orthologs
    10
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIM5, tripartite motif containing 5
  • Synonyms
    RNF88, TRIM5alpha
  • Links
    NCBI Gene ID: 85363
    neXtProt AC: NX_Q9C035
    UniProt: Q9C035

  • Chr Location
    11p15.4; chr11:5588635-5938619 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    35
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    729
  • Tissues
    14
  • cDNA Data
    33
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000057143 Ensembl Gene Model | MGI Sequence Detail 14609 C57BL/6J ±  kb
transcript ENSMUST00000059037 Ensembl | MGI Sequence Detail 3740 Not Applicable  
polypeptide ENSMUSP00000060100 Ensembl | MGI Sequence Detail 497 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 33
    cDNA 33

    Microarray probesets 3
Other
Accession IDs
less
MGI:2441735
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:287707 Chang TH, et al., Tripartite Motif (TRIM) 12c, a Mouse Homolog of TRIM5, Is a Ubiquitin Ligase That Stimulates Type I IFN and NF-kappaB Pathways along with TNFR-Associated Factor 6. J Immunol. 2015 Dec 1;195(11):5367-79
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory