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Traj18 Gene Detail
Summary
  • Symbol
    Traj18
  • Name
    T cell receptor alpha joining 18
  • Synonyms
    Gm17009
Location &
Maps
more
  • Sequence Map
    Chr14:54200777-54200842 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 27.69 cM
Strain
Comparison
more
  • SNPs within 2kb
    31 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4440521
gene segment Chr14:54200777-54200842 (+)
129S1/SvImJ MGP_129S1SvImJ_G0002472
gene segment Chr14:48129050-48129115 (+)
A/J MGP_AJ_G0002446
gene segment Chr14:47220999-47221064 (+)
AKR/J MGP_AKRJ_G0002432
gene segment Chr14:48929990-48930055 (+)
BALB/cJ MGP_BALBcJ_G0002440
gene segment Chr14:47189781-47189846 (+)
C3H/HeJ MGP_C3HHeJ_G0002419
gene segment Chr14:48610722-48610787 (+)
C57BL/6NJ MGP_C57BL6NJ_G0002567
gene segment Chr14:50594537-50594602 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0002165
gene segment Chr14:45633623-45633688 (+)
CAST/EiJ MGP_CASTEiJ_G0002381
gene segment Chr14:44842941-44843006 (+)
CBA/J MGP_CBAJ_G0002410
gene segment Chr14:52088192-52088257 (+)
DBA/2J MGP_DBA2J_G0002415
gene segment Chr14:46965162-46965227 (+)
FVB/NJ MGP_FVBNJ_G0002429
gene segment Chr14:46419448-46419513 (+)
LP/J MGP_LPJ_G0002469
gene segment Chr14:49158696-49158761 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0002399
gene segment Chr14:51530141-51530206 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0002562
gene segment Chr14:48111724-48111789 (+)
PWK/PhJ MGP_PWKPhJ_G0002342
gene segment Chr14:43488751-43488816 (+)
SPRET/EiJ MGP_SPRETEiJ_G0002294
gene segment Chr14:44088640-44088705 (+)
WSB/EiJ MGP_WSBEiJ_G0002408
gene segment Chr14:48403546-48403611 (+)



Homology
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Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotypes from 2 alleles in 3 genetic backgrounds
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit an absence of invariant NK T cells and reduced response to induced pulmonary inflammation.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    • All Sequences
    • RefSeq
    • UniProt
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 100124371 NCBI Gene Model | MGI Sequence Detail 66 C57BL/6J ±  kb
    polypeptide A0A0G2JG46 UniProt | EBI | MGI Sequence Detail 22 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • PDB
    References
    more
    • Summaries
      All 11
      Gene Ontology 1
      Phenotypes 5
    • Earliest
      J:101719 Khor B, et al., Chromosomal excision of TCRdelta chain genes is dispensable for alphabeta T cell lineage commitment. Int Immunol. 2005 Mar;17(3):225-32
    • Latest
      J:258615 Liew PX, et al., iNKT Cells Orchestrate a Switch from Inflammation to Resolution of Sterile Liver Injury. Immunity. 2017 Oct 17;47(4):752-765.e5

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    09/22/2020
    MGI 6.16
    The Jackson Laboratory