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Ighv5-12 Gene Detail
Summary
  • Symbol
    Ighv5-12
  • Name
    immunoglobulin heavy variable 5-12
  • Synonyms
    Gm16592
  • Feature Type
    gene segment
  • IDs
    MGI:4439516
    NCBI Gene: 668395
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:113665746-113666039 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 62.16 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4439516
gene segment Chr12:113665744-113666198 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0000042
gene segment Chr12:115455899-115456358 (-)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0000044
gene segment Chr12:110095342-110095801 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0000048
gene segment Chr12:127597243-127597697 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0000055
gene segment Chr12:114537603-114538062 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0000037
gene segment Chr12:108676299-108676758 (-)
WSB/EiJ MGP_WSBEiJ_G0000050
gene segment Chr12:115590664-115591121 (-)



Homology
more
  • Human Ortholog
    IGHV3-11, immunoglobulin heavy variable 3-11
  • Vertebrate Orthologs
    15
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGHV3-11, immunoglobulin heavy variable 3-11
  • Synonyms
    IGHV311, VH
  • Links
    NCBI Gene ID: 28450
    UniProt: P01762

  • Chr Location
    14q32.33; chr14:106116635-106117084 (-)  GRCh38.p7

  • Human Ortholog
    IGHV3-13, immunoglobulin heavy variable 3-13
  • Synonyms
    IGHV313
  • Links
    NCBI Gene ID: 28449
    UniProt: P01766

  • Chr Location
    14q32.33; chr14:106129540-106129992 (-)  GRCh38.p7

  • Human Ortholog
    IGHV3-20, immunoglobulin heavy variable 3-20
  • Synonyms
    IGHV320, VH
  • Links
    NCBI Gene ID: 28445
    UniProt: A0A0C4DH32

  • Chr Location
    14q32.33; chr14:106210936-106211391 (-)  GRCh38.p7

  • Human Ortholog
    IGHV3-21, immunoglobulin heavy variable 3-21
  • Synonyms
    IGHV321, VH
  • Links
    NCBI Gene ID: 28444
    UniProt: A0A0B4J1V1

  • Chr Location
    14q32.33; chr14:106235062-106235515 (-)  GRCh38.p7

  • Human Ortholog
    IGHV3-23, immunoglobulin heavy variable 3-23
  • Synonyms
    DP47, IGHV323, V3-23, VH26
  • Links
    NCBI Gene ID: 28442
    UniProt: P01764

  • Chr Location
    14q32.33; chr14:106268606-106269061 (-)  GRCh38.p7

  • Human Ortholog
    IGHV3-30, immunoglobulin heavy variable 3-30
  • Synonyms
    IGHV330, VH
  • Links
    NCBI Gene ID: 28439
    UniProt: P01768

  • Chr Location
    14q32.33; chr14:106335080-106335533 (-)  GRCh38.p7

  • Human Ortholog
    IGHV3-33, immunoglobulin heavy variable 3-33
  • Synonyms
    IGHV333, VH
  • Links
    NCBI Gene ID: 28434
    UniProt: P01772

  • Chr Location
    14q32.33; chr14:106359791-106360244 (-)  GRCh38.p7

  • Human Ortholog
    IGHV3-43, immunoglobulin heavy variable 3-43
  • Synonyms
    IGHV343, VH
  • Links
    NCBI Gene ID: 28426
    UniProt: A0A0B4J1X8

  • Chr Location
    14q32.33; chr14:106470263-106470720 (-)  GRCh38.p7

  • Human Ortholog
    IGHV3-48, immunoglobulin heavy variable 3-48
  • Synonyms
    IGHV348, VH
  • Links
    NCBI Gene ID: 28424
    UniProt: P01763

  • Chr Location
    14q32.33; chr14:106537810-106538265 (-)  GRCh38.p7

  • Human Ortholog
    IGHV3-53, immunoglobulin heavy variable 3-53
  • Synonyms
    IGHV353, VH
  • Links
    NCBI Gene ID: 28420
    UniProt: P01767

  • Chr Location
    14q32.33; chr14:106592676-106593126 (-)  GRCh38.p7

  • Human Ortholog
    IGHV3-64, immunoglobulin heavy variable 3-64
  • Synonyms
    IGHV364, VH
  • Links
    NCBI Gene ID: 28414
    UniProt: A0A075B6Q5

  • Chr Location
    14q32.33; chr14:106657723-106658178 (-)  GRCh38.p7

  • Human Ortholog
    IGHV3-64D, immunoglobulin heavy variable 3-64D
  • Links
    NCBI Gene ID: 102723170
    UniProt: A0A0J9YX35

  • Chr Location
    14q32.33; chr14:106088083-106088573 (-)  GRCh38.p7

  • Human Ortholog
    IGHV3-66, immunoglobulin heavy variable 3-66
  • Synonyms
    IGHV366, VH
  • Links
    NCBI Gene ID: 28412
    UniProt: A0A0C4DH42

  • Chr Location
    14q32.33; chr14:106675015-106675465 (-)  GRCh38.p7

  • Human Ortholog
    IGHV3-7, immunoglobulin heavy variable 3-7
  • Synonyms
    IGHV37, VH
  • Links
    NCBI Gene ID: 28452
    UniProt: P01780

  • Chr Location
    14q32.33; chr14:106062149-106062604 (-)  GRCh38.p7

  • Human Ortholog
    IGHV3-74, immunoglobulin heavy variable 3-74
  • Synonyms
    IGHV374, VH
  • Links
    NCBI Gene ID: 28408
    UniProt: A0A0B4J1X5

  • Chr Location
    14q32.33; chr14:106810440-106810895 (-)  GRCh38.p7

Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 668395 NCBI Gene Model | MGI Sequence Detail 294 C57BL/6J ±  kb
transcript U23092 GenBank | ENA | DDBJ | MGI Sequence Detail 319 C.BKa-Prkdc  
polypeptide A0A075B5Q4 UniProt | EBI | MGI Sequence Detail 117 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1
References
more
  • Summaries
    All 8
    Gene Ontology 1
  • Earliest
    J:161658 Essen LO, et al., 1.3 A X-ray structure of an antibody Fv fragment used for induced membrane-protein crystallization. Acta Crystallogr D Biol Crystallogr. 2003 Apr;59(Pt 4):677-87
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/12/2021
MGI 6.17
The Jackson Laboratory