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Dp(7Herc2-Mkrn3)1Taku Cytogenetic Marker Detail
Summary
  • Symbol
    Dp(7Herc2-Mkrn3)1Taku
  • Name
    duplication, Chr 7, Toru Takumi 1
  • Feature Type
    chromosomal duplication
  • IDs
    MGI:4359727
Location &
Maps
more
  • Sequence Map
    Chr7:55699944-62069887 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, Syntenic
Human Diseases
more
  • Diseases
    1 with Dp(7Herc2-Mkrn3)1Taku mouse models

Human Disease Mouse Models
      
IDs
 View 3 models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    19 phenotypes from 1 allele in 3 genetic backgrounds
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
References
more
  • Summaries
    All 17
    Diseases 3
    Phenotypes 17
  • Earliest
    J:151648 Nakatani J, et al., Abnormal behavior in a chromosome-engineered mouse model for human 15q11-13 duplication seen in autism. Cell. 2009 Jun 26;137(7):1235-46
  • Latest
    J:335224 Nakai N, et al., Virtual reality-based real-time imaging reveals abnormal cortical dynamics during behavioral transitions in a mouse model of autism. Cell Rep. 2023 Mar 24;:112258
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory