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Dp(7Herc2-Mkrn3)1Taku Cytogenetic Marker Detail
Summary
  • Symbol
    Dp(7Herc2-Mkrn3)1Taku
  • Name
    duplication, Chr 7, Toru Takumi 1
  • Feature Type
    chromosomal duplication
  • IDs
    MGI:4359727
Location & Maps
more
  • Genetic Map
    Chromosome 7, Syntenic
Human Diseases
more
  • Diseases
    2 with Dp(7Herc2-Mkrn3)1Taku mouse models

Human Disease Mouse Models
       Autism   OMIM: 209850 View 1 model
Chromosome 15q11-Q13 Duplication Syndrome   OMIM: 608636 View 3 models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    6 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    19 phenotypes from 1 allele in 3 genetic backgrounds
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    1
  • Targeted
    1
References
more
  • Summaries
    All 7
    Diseases 6
    Phenotypes 7
  • Earliest
    J:151648 Nakatani J, et al., Abnormal behavior in a chromosome-engineered mouse model for human 15q11-13 duplication seen in autism. Cell. 2009 Jun 26;137(7):1235-46
  • Latest
    J:223931 Kishimoto R, et al., Model mice for 15q11-13 duplication syndrome exhibit late-onset obesity and altered lipid metabolism. Hum Mol Genet. 2015 Aug 15;24(16):4559-72

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory