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Methig1 Gene Detail
Summary
  • Symbol
    Methig1
  • Name
    methyltransferase hypoxia inducible domain containing 1
  • Synonyms
    AB099516, Mettl7a2Higd1c, Mettl7a2-Higd1c, UbiE2-Hig1-4, UbiE-YGHL1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3845761
    NCBI Gene: 554292
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr15:100353200-100384435 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 56.27 cM
Strain
Comparison
more
  • SNPs within 2kb
    228 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3845761
protein coding gene Chr15:100353149-100384436 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0022311
protein coding gene Chr15:98217404-98307979 (+)
AKR/J MGP_AKRJ_G0022287
protein coding gene Chr15:101281686-101311641 (+)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0022083
protein coding gene Chr15:101295272-101391557 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022762
protein coding gene Chr15:106129528-106180738 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020285
protein coding gene Chr15:94046998-94048054 (+)
CAST/EiJ MGP_CASTEiJ_G0021607
protein coding gene Chr15:102136892-102249207 (+)
CBA/J MGP_CBAJ_G0022051
protein coding gene Chr15:109766101-109827842 (+)
DBA/2J MGP_DBA2J_G0022181
protein coding gene Chr15:97644034-97675787 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0022249
protein coding gene Chr15:102380918-102516434 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022178
protein coding gene Chr15:113517177-113552415 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022774
protein coding gene Chr15:101285355-101319703 (+)
PWK/PhJ MGP_PWKPhJ_G0021347
protein coding gene Chr15:97769985-97801511 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021181
protein coding gene Chr15:101142878-101214021 (+)
WSB/EiJ MGP_WSBEiJ_G0021657
protein coding gene Chr15:101819496-101946849 (+)



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    19 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Genomic Mutations
    3 involving Methig1
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 554292 NCBI Gene Model | MGI Sequence Detail 31236 C57BL/6J ±  kb
transcript NM_001024672 RefSeq | MGI Sequence Detail 1449 C57BL/6  
polypeptide NP_001019843 RefSeq | MGI Sequence Detail 264 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR007667 Hypoxia induced protein, domain
    IPR013216 Methyltransferase type 11
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 32
    Diseases 1
    Gene Ontology 1
    Phenotypes 19
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory